GPC2 - glypican 2 Gene

Homo sapiens

Gene ID: 221914 | Gene type: protein coding

About GPC2

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,169,606-100,177,381 (from NCBI)

This gene has 5 transcripts (splice variants), 190 orthologues and 5 paralogues. Biased expression in testis (RPKM 5.5), skin (RPKM 2.9) and 7 other tissues.

Summary

Predicted to be involved in several processes, including positive regulation of neuron projection development; regulation of protein localization to membrane; and smoothened signaling pathway. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

GPC2 Products(1)

mRNA	Protein	Name
NM_152742.3	NP_689955.1	glypican-2 precursor

GPC2 Protein Structure

Glypican

0
100
200
300
400
500
579 a.a.

Protein Preferred Names

Protein Names

glypican-2

cerebroglycan proteoglycan

Recombinant GPC2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P78727	Glypican-2/GPC2 Protein, Human (HEK293, His)	Q8N158 (S24-G554)	≥95%
HY-P78735	Glypican-2/GPC2 Protein, Human (HEK293, Fc)	Q8N158 (S24-S553)	≥95%

Related Diseases

Diseases

Alias

Keipert Syndrome

Nasodigitoacoustic Syndrome	KPTS
Nasodigitoacoustic Syndrome, Formerly

Omodysplasia

Omodysplasia Type 1

Omodysplasia 2

Central Corneal Ulcer

Simpson-Golabi-Behmel Syndrome, Type 1

Simpson-Golabi-Behmel Syndrome Type 1	Simpson-Golabi-Behmel Syndrome
SGBS1	Golabi-Rosen Syndrome
Simpson Dysmorphia Syndrome	Sgbs
Bulldog Syndrome	Dgsx
Sdys	Dysplasia Gigantism Syndrome, X-Linked
X-Linked Dysplasia Gigantism Syndrome	Dgsx Golabi-Rosen Syndrome
Sara Angers Syndrome	Sgb Syndrome
Mental Retardation-Overgrowth Syndrome	Simpson Dysplasia Syndrome
Simpson Syndrome	Simpson-Golabi-Behmel Syndrome 1
Dysplasia Gigantism Syndrome X-Linked

Hereditary Multiple Exostoses

Multiple Congenital Exostosis	Hereditary Multiple Exostoses 1
Hereditary Multiple Exostoses 2	Hereditary Multiple Exostoses 3
Multiple Exostosis Syndromes	Multiple Ostechondromas
Osteochondromatosis Syndrome	Exostoses Multiple Hereditary
Exostoses, Multiple Hereditary

Saul-Wilson Syndrome

Microcephalic Osteodysplastic Dysplasia	Microcephalic Osteodysplastic Dysplasia, Saul-Wilson Type
SWILS	Microcephalic Osteodysplastic Dysplasia Saul Wilson Type

Exostosis

Osteophyte	Exostoses
Orbital Exostosis	Exostosis Of Orbit
Bone Spur	Bony Outgrowth
Swimmer'S Exostosis	Osteophytes
External Exotoses	Cartilaginous Exostosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05627	GPC2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	GPC2	VGNC	VGNC:41372
Bos taurus	GPC2	VGNC	VGNC:29524
Macaca mulatta	GPC2	VGNC	VGNC:108411
Felis catus	GPC2	VGNC	VGNC:67404
Rattus norvegicus	GPC2	RGD	RGD:621363
Mus musculus	GPC2	MGD	MGI:1919201
Others	GPC2	NCBI