Pim3 - proviral integration site 3 Gene

Mus musculus

Also known as Kid1

Gene ID: 223775 | Gene type: protein coding

About Pim3

Chromosome 15: 88,746,389-88,749,929 forward strand.GRCm39:CM001008.3

This gene has 2 transcripts (splice variants), 220 orthologues, 2 paralogues and is associated with 1 phenotype. Broad expression in adrenal adult (RPKM 73.4), duodenum adult (RPKM 37.2) and 26 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Involved in negative regulation of Insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in spleen. Orthologous to human PIM3 (Pim-3 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Pim3 Products(1)

mRNA	Protein	Name
NM_145478.2	NP_663453.1	serine/threonine-protein kinase pim-3

Pim3 Protein Structure

PKc_like

0
100
200
300
326 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase pim-3

KID-1/kinase induced by depolarization

Related Agents

Clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Phase
HY-101870B	Uzansertib phosphate	Inhibitor	99.39%	Phase 2
HY-19322B	PIM-447 dihydrochloride	Inhibitor	99.94%	Phase 1
HY-19322	PIM447	Inhibitor	99.78%	Phase 1

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-16976	GDC-0339	Inhibitor	99.77%	Unkown
HY-120758	SEL24-B489	Inhibitor	98.58%	Unkown
HY-111552	PIM1-IN-1	Inhibitor	99.51%	Unkown
HY-122665	HTH-01-091	Inhibitor	98.64%	Unkown
HY-101870	Uzansertib	Inhibitor	/	Unkown
HY-101783	GNE-955	Inhibitor	/	Unkown
HY-123983	HS56	Inhibitor	/	Unkown
HY-163442A	PIM3-IN-1 hydrochloride	Inhibitor	/	Unkown
HY-142696	CDK6/PIM1-IN-1	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pim3	NCBI	NCBI:415116

Name
Email *

	Sorry, but the email address you supplied was invalid.