CD93 - CD93 molecule Gene

Homo sapiens

Also known as C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1

Gene ID: 22918 | Gene type: protein coding

About CD93

Cytogenetic location: 20p11.21 Genomic coordinates (GRCh38): 20:23,079,360-23,086,324 (from NCBI)

This gene has 1 transcript (splice variant), 266 orthologues and 8 paralogues. Broad expression in placenta (RPKM 64.0), lung (RPKM 47.5) and 21 other tissues.

Summary

The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the Cytoskeleton and in the remodelling of the Cytoskeleton. [provided by RefSeq, Jul 2008]

CD93 Products(1)

mRNA	Protein	Name
NM_012072.4	NP_036204.2	complement component C1q receptor precursor

CD93 Protein Structure

Lectin_C

cEGF

EGF_CA

0
100
200
300
400
500
600
652 a.a.

Protein Preferred Names

Protein Names

complement component C1q receptor

C1q receptor 1

Recombinant CD93 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7691	CD93/C1qR1 Protein, Human (HEK293, His)	Q9NPY3 (A24-K580)	≥95%
HY-P78098	CD93/C1qR1 Protein, Human (Biotinylated, HEK293, His-Avi)	Q9NPY3 (T22-K580)	≥95%

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02278	CD93 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CD93	VGNC	VGNC:80061
Macaca mulatta	CD93	VGNC	VGNC:70725
Rattus norvegicus	CD93	RGD	RGD:621251
Canis familiaris	CD93	VGNC	VGNC:58296
Bos taurus	CD93	VGNC	VGNC:52749
Mus musculus	CD93	MGD	MGI:106664
Macaca fascicularis	CD93	NCBI
Others	CD93	NCBI