2. Gene
  3. CLCC1 - chloride channel CLIC like 1 Gene

CLCC1 - chloride channel CLIC like 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MCLC; RP32

Gene ID: 23155 | Gene type: protein coding

About CLCC1

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:108,929,505-108,963,484 (from NCBI)

This gene has 88 transcripts (splice variants), 119 orthologues and is associated with 2 phenotypes. Ubiquitous expression in brain (RPKM 9.3), thyroid (RPKM 9.3) and 25 other tissues.

Summary

Predicted to enable Chloride Channel activity. Predicted to be involved in chloride transport. Located in endoplasmic reticulum and mitochondria-associated endoplasmic reticulum membrane. Implicated in retinitis pigmentosa 32. [provided by Alliance of Genome Resources, Apr 2022]

CLCC1 Products(17)

mRNA Protein Name
NM_001048210.3 NP_001041675.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001278202.2 NP_001265131.1 chloride channel CLIC-like protein 1 isoform 3 precursor
NM_001278203.1 NP_001265132.1 chloride channel CLIC-like protein 1 isoform 4 precursor
NM_001377458.1 NP_001364387.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377459.1 NP_001364388.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377460.1 NP_001364389.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377461.1 NP_001364390.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377462.1 NP_001364391.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377463.1 NP_001364392.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377464.1 NP_001364393.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377465.1 NP_001364394.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377466.1 NP_001364395.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377467.1 NP_001364396.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377468.1 NP_001364397.1 chloride channel CLIC-like protein 1 isoform 1 precursor
NM_001377469.1 NP_001364398.1 chloride channel CLIC-like protein 1 isoform 5 precursor
NM_001377470.1 NP_001364399.1 chloride channel CLIC-like protein 1 isoform 6
NM_015127.5 NP_055942.1 chloride channel CLIC-like protein 1 isoform 2 precursor

CLCC1 Protein Structure

MCLC

MCLC: Mid-1-related chloride channel (MCLC) (3 - 551)

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  • 551 a.a.
Protein Preferred Names Protein Names

chloride channel CLIC-like protein 1

Mid-1-related chloride channel protein 1

Related Diseases

Diseases Alias
Retinitis Pigmentosa 32

RP32

Retinitis Pigmentosa-32
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02751 CLCC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CLCC1 VGNC VGNC:39299
Rattus norvegicus CLCC1 RGD RGD:708359
Bos taurus CLCC1 VGNC VGNC:27394
Felis catus CLCC1 VGNC VGNC:60921
Mus musculus CLCC1 MGD MGI:2385186
Macaca mulatta CLCC1 VGNC VGNC:71373