SCFD1 - sec1 family domain containing 1 Gene

Homo sapiens

Also known as SLY1; RA410; SLY1P; STXBP1L2; C14orf163

Gene ID: 23256 | Gene type: protein coding

About SCFD1

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:30,622,254-30,735,850 (from NCBI)

This gene has 72 transcripts (splice variants), 213 orthologues and 7 paralogues. Ubiquitous expression in thyroid (RPKM 19.4), testis (RPKM 13.5) and 25 other tissues.

Summary

Predicted to enable syntaxin binding activity. Involved in negative regulation of autophagosome assembly; regulation of protein transport; and response to toxic substance. Located in cis-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]

SCFD1 Products(6)

mRNA	Protein	Name
NM_001257376.1	NP_001244305.1	sec1 family domain-containing protein 1 isoform c
NM_001283031.1	NP_001269960.1	sec1 family domain-containing protein 1 isoform d
NM_001283032.1	NP_001269961.1	sec1 family domain-containing protein 1 isoform e
NM_001283033.1	NP_001269962.1	sec1 family domain-containing protein 1 isoform d
NM_016106.4	NP_057190.2	sec1 family domain-containing protein 1 isoform a
NM_182835.2	NP_878255.1	sec1 family domain-containing protein 1 isoform b

SCFD1 Protein Structure

Sec1

0
100
200
300
400
500
600
642 a.a.

Protein Preferred Names

Protein Names

sec1 family domain-containing protein 1

syntaxin-binding protein 1-like 2

Related Diseases

Diseases

Alias

Familial Adenomatous Polyposis 3

FAP3	Nthl1-Related Attenuated Familial Adenomatous Polyposis
Nthl1-Related Afap	Nthl1-Related Attenuated Fap

Achondrogenesis, Type Ia

Achondrogenesis Type Ia	Achondrogenesis Type 1a
ACG1A	Achondrogenesis, Houston-Harris Type
Achondrogenesis Houston-Harris Type	Achondrogenesis 1a
Acg-Ia

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis	ALS
Lou Gehrig Disease	Amyotrophic Lateral Sclerosis Type 1
Charcot Disease	ALS1
Amyotrophic Lateral Sclerosis, Susceptibility To	Fals
Lou Gehrig'S Disease	Mnd
Motor Neuron Disease	Familial Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial	Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Bulbar	Motor Neurone Disease
Amyotrophic Lateral Sclerosis With Dementia	Dementia With Amyotrophic Lateral Sclerosis
Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Sclerosis, Lateral, Amyotrophic
Sclerosis, Lateral, Amyotrophic, Type 1	Amyotrophic Sclerosis
Als - [Amyotrophic Lateral Sclerosis]	Wasting Palsy
Amyotrophic Paralysis	Amyotrophy Lateral Sclerosis
Wasting Paralysis	Spinal Progressive Amyotrophy
Progressive Atrophic Paralysis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12499	SCFD1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SCFD1	VGNC	VGNC:64907
Rattus norvegicus	SCFD1	RGD	RGD:619828
Bos taurus	SCFD1	VGNC	VGNC:34330
Mus musculus	SCFD1	MGD	MGI:1924233
Macaca mulatta	SCFD1	VGNC	VGNC:77065
Canis familiaris	SCFD1	VGNC	VGNC:45903

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