ICE1 - interactor of little elongation complex ELL subunit 1 Gene

Homo sapiens

Also known as KIAA0947

Gene ID: 23379 | Gene type: protein coding

About ICE1

Cytogenetic location: 5p15.32 Genomic coordinates (GRCh38): 5:5,422,677-5,490,220 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 7.5), brain (RPKM 7.4) and 25 other tissues.

Summary

Enables protein-macromolecule adaptor activity. Involved in several processes, including positive regulation of intracellular protein transport; positive regulation of transcription by RNA polymerase III; and snRNA transcription. Located in Cajal body; histone locus body; and transcriptionally active chromatin. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022]

ICE1 Products(1)

mRNA	Protein	Name
NM_015325.3	NP_056140.1	little elongation complex subunit 1

Protein Preferred Names

Protein Names

little elongation complex subunit 1

interactor of little elongator complex ELL subunit 1

Related Diseases

Diseases

Alias

Cri-Du-Chat Syndrome

5p Deletion Syndrome	5p Partial Monosomy Syndrome
Monosomy 5p	Cat Cry Syndrome
Chromosome 5p Deletion Syndrome	Cri Du Chat Syndrome
5p- Syndrome	5p Minus Syndrome
Chromosome 5p- Syndrome	Chromosome 5 Short Arm Deletion Syndrome
Chromosome 5p Deletion	Deletion 5p
Cri Du Chat	5p Partial Deletion Syndrome
Partial Deletion Of Short Arm Of Chromosome 5 Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06517	ICE1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ICE1	RGD	RGD:1309747
Canis familiaris	ICE1	VGNC	VGNC:41858
Mus musculus	ICE1	MGD	MGI:2385865
Bos taurus	ICE1	VGNC	VGNC:30026
Macaca mulatta	ICE1	VGNC	VGNC:73457
Felis catus	ICE1	VGNC	VGNC:62867

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