1. Gene
  2. Hrh2 - histamine receptor H 2 Gene

Hrh2 - histamine receptor H 2 Gene

Rattus norvegicus

Also known as H2R; HH2R

Gene ID: 25461 | Gene type: protein coding

About Hrh2

Primary_assembly 17: 10,368,298-10,407,631 reverse strand.mRatBN7.2:CM026990.1

This gene has 1 transcript (splice variant), 249 orthologues, 35 paralogues and is associated with 11 phenotypes. Biased expression in Brain (RPKM 17.7), Spleen (RPKM 8.2) and 7 other tissues.

Summary

Enables heterocyclic compound binding activity and Histamine Receptor activity. Involved in cellular response to histamine and negative regulation of arachidonic acid secretion. Located in membrane. Biomarker of transient cerebral ischemia. Orthologous to human HRH2 (Histamine Receptor H2). [provided by Alliance of Genome Resources, Apr 2022]

Hrh2 Products(1)

mRNA Protein Name
NM_001413011.1 NP_001399940.1 histamine H2 receptor

Hrh2 Protein Structure

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (18 - 297)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (19 - 45)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (52 - 79)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (90 - 120)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (132 - 152)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (177 - 207)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (225 - 255)

7tmA_Histamine_H2R

7tmA_Histamine_H2R: cd15051 (265 - 290)

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  • 413 a.a.
Protein Preferred Names Protein Names

histamine H2 receptor

gastric receptor I

Orthologs Information

Species Symbol Source ID
Homo sapiens Hrh2 NCBI NCBI:3274