2. Gene
  3. DCAF12 - DDB1 and CUL4 associated factor 12 Gene

DCAF12 - DDB1 and CUL4 associated factor 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CT102; TCC52; WDR40A; KIAA1892

Gene ID: 25853 | Gene type: protein coding

About DCAF12

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:34,086,387-34,126,698 (from NCBI)

This gene has 5 transcripts (splice variants), 204 orthologues and 2 paralogues. Broad expression in testis (RPKM 38.2), lymph node (RPKM 19.3) and 25 other tissues.

Summary

This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 Ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. [provided by RefSeq, Jul 2009]

DCAF12 Products(1)

mRNA Protein Name
NM_015397.4 NP_056212.1 DDB1- and CUL4-associated factor 12

DCAF12 Protein Structure

WD40

WD40: WD domain, G-beta repeat (181 - 211)

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  • 453 a.a.
Protein Preferred Names Protein Names

DDB1- and CUL4-associated factor 12

WD repeat domain 40A

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03559 DCAF12 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DCAF12 VGNC VGNC:61355
Bos taurus DCAF12 VGNC VGNC:27901
Mus musculus DCAF12 MGD MGI:1916220
Macaca mulatta DCAF12 VGNC VGNC:71678
Rattus norvegicus DCAF12 RGD RGD:1594034
Canis familiaris DCAF12 VGNC VGNC:39790