2. Gene
  3. FGF22 - fibroblast growth factor 22 Gene

FGF22 - fibroblast growth factor 22 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 27006 | Gene type: protein coding

About FGF22

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:639,879-644,373 (from NCBI)

This gene has 3 transcripts (splice variants), 182 orthologues and 21 paralogues. Biased expression in skin (RPKM 1.5), brain (RPKM 0.4) and 7 other tissues.

Summary

The protein encoded by this gene is a member of the Fibroblast Growth Factor (FGF) family. FGF Family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

FGF22 Products(2)

mRNA Protein Name
NM_001300812.3 NP_001287741.1 fibroblast growth factor 22 isoform 2 precursor
NM_020637.2 NP_065688.1 fibroblast growth factor 22 isoform 1 precursor

FGF22 Protein Structure

FGF

FGF: Fibroblast growth factor (41 - 165)

  • 0
  • 100
  • 170 a.a.
Protein Preferred Names Protein Names

fibroblast growth factor 22

FGF-22

Recombinant FGF22 Proteins

Cat. No. Product Name Accession Purity
HY-P79140 FGF-22 Protein, Human (His) Q9HCT0 (T23-S170) ≥95%
HY-P700063AF Animal-Free FGF-22 Protein, Human (His) Q9HCT0 (T23-S170) ≥95%
HY-P700494 FGF-22 Protein, Human (His-SUMO) Q9HCT0 (T23-S170) ≥95%

Related Diseases

Diseases Alias
Breast Giant Fibroadenoma

Giant Fibroadenoma

Giant Fibroadenoma Of Breast
Lacrimoauriculodentodigital Syndrome

Ladd Syndrome

Levy-Hollister Syndrome

Lacrimo-Auriculo-Dento-Digital Syndrome

LADD

Lacrimoauriculodento-Digital Syndrome

Levy Hollister Syndrome

Lard Syndrome

Lacrimoauriculoradiodental Syndrome

LADDS

Congenital Duodenal Obstruction Due To Malrotation Of Intestine
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148432 FGF22-IN-1 Inhibitor 98.07% Unkown
HY-RS04899 FGF22 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FGF22 MGD MGI:1914362
Canis familiaris FGF22 VGNC VGNC:40849
Macaca mulatta FGF22 VGNC VGNC:72648
Bos taurus FGF22 VGNC VGNC:52233
Felis catus FGF22 VGNC VGNC:102584
Rattus norvegicus FGF22 RGD RGD:620177
Others FGF22 NCBI