Nlrx1 - NLR family member X1 Gene

Mus musculus

Also known as NOD9

Gene ID: 270151 | Gene type: protein coding

About Nlrx1

Chromosome 9: 44,164,014-44,179,896 reverse strand.GRCm39:CM001002.3

This gene has 6 transcripts (splice variants), 193 orthologues, 22 paralogues and is associated with 13 phenotypes. Ubiquitous expression in colon adult (RPKM 11.8), adrenal adult (RPKM 1.3) and 27 other tissues.

Summary

Predicted to enable ATP binding activity. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of cytokine production; and negative regulation of defense response. Located in mitochondrion. Orthologous to human NLRX1 (NLR family member X1). [provided by Alliance of Genome Resources, Apr 2022]

Nlrx1 Products(3)

mRNA	Protein	Name
NM_178420.3	NP_848507.2	NLR family member X1
NM_001163742.1	NP_001157214.1	NLR family member X1
NM_001163743.1	NP_001157215.1	NLR family member X1

Nlrx1 Protein Structure

P-loop_NTPase

LRR_RI

PPP1R42

LRR_RI

0
200
400
600
800
975 a.a.

Protein Preferred Names

Protein Names

NLR family member X1

nucleotide-binding domain and leucine-rich repeat containing

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-141521	Amelenodor	Activator	98.47%	Phase 1

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09365	NLRX1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09366	Nlrx1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09367	Nlrx1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nlrx1	NCBI	NCBI:79671

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