GSDMA - gasdermin A Gene

Homo sapiens

Also known as GSDM; FKSG9; GSDM1

Gene ID: 284110 | Gene type: protein coding

About GSDMA

Cytogenetic location: 17q21.1 Genomic coordinates (GRCh38): 17:39,963,004-39,977,768 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 4 paralogues. Biased expression in skin (RPKM 16.4) and esophagus (RPKM 1.0).

Summary

Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Involved in apoptotic process. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

GSDMA Products(1)

mRNA	Protein	Name
NM_178171.5	NP_835465.2	gasdermin-A

GSDMA Protein Structure

Gasdermin

0
100
200
300
400
445 a.a.

Protein Preferred Names

Protein Names

gasdermin-A

gasdermin-1

Related Diseases

Diseases

Alias

Inflammatory Bowel Disease 22

IBD22

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Childhood-Onset Asthma

Childhood Asthma

Asthma Childhood

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05854	GSDMA Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GSDMA	RGD	RGD:1592062
Felis catus	GSDMA	VGNC	VGNC:62725
Macaca mulatta	GSDMA	VGNC	VGNC:104606
Bos taurus	GSDMA	VGNC	VGNC:49998
Canis familiaris	GSDMA	VGNC	VGNC:54951

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