2. Gene
  3. PRMT6 - protein arginine methyltransferase 6 Gene

PRMT6 - protein arginine methyltransferase 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hrmt1l6

Gene ID: 295384 | Gene type: protein coding

About PRMT6

Primary_assembly 2: 197,927,220-197,933,648 reverse strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 166 orthologues, 10 paralogues and is associated with 2 phenotypes. Biased expression in Thymus (RPKM 33.4), Spleen (RPKM 33.1) and 9 other tissues.

Summary

Predicted to enable chromatin binding activity; histone binding activity; and protein-arginine N-methyltransferase activity. Predicted to be involved in negative regulation of nitrogen compound metabolic process; protein methylation; and regulation of mitochondrion organization. Predicted to act upstream of or within several processes, including cellular senescence; histone H3-R2 methylation; and negative regulation of nitrogen compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Orthologous to human PRMT6 (protein arginine methyltransferase 6). [provided by Alliance of Genome Resources, Apr 2022]

PRMT6 Products(2)

mRNA Protein Name
NM_001393859.1 NP_001380788.1 protein arginine N-methyltransferase 6
NM_001393858.1 NP_001380787.1 protein arginine N-methyltransferase 6

PRMT6 Protein Structure

AdoMet_MTases

AdoMet_MTases: cd02440 (84 - 184)

  • 0
  • 100
  • 200
  • 300
  • 375 a.a.
Protein Preferred Names Protein Names

protein arginine N-methyltransferase 6

HMT1 hnRNP methyltransferase-like 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19615 MS023 Inhibitor 99.73% Unkown
HY-114965 TP-064 Inhibitor 98.35% Unkown
HY-12970A EPZ020411 hydrochloride Inhibitor 98.15% Unkown
HY-12970 EPZ020411 Inhibitor 98.06% Unkown
HY-19615B MS023 dihydrochloride Inhibitor 99.78% Unkown
HY-100360 MS049 Inhibitor ≥98.0% Unkown
HY-133740 MS117 Inhibitor ≥98.0% Unkown
HY-128717B GSK3368715 trihydrochloride Inhibitor / Unkown
HY-146810 PRMT4-IN-1 Inhibitor / Unkown
HY-100565A SGC2085 hydrochloride Inhibitor / Unkown
HY-161334 CARM1-IN-4 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PRMT6 NCBI NCBI:55170