2. Gene
  3. CYP2S1 - cytochrome P450 family 2 subfamily S member 1 Gene

CYP2S1 - cytochrome P450 family 2 subfamily S member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CYPIIS1

Gene ID: 29785 | Gene type: protein coding

About CYP2S1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,193,219-41,207,539 (from NCBI)

This gene has 6 transcripts (splice variants), 90 orthologues and 15 paralogues. Biased expression in stomach (RPKM 58.7), duodenum (RPKM 46.6) and 7 other tissues.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. [provided by RefSeq, Jul 2008]

CYP2S1 Products(1)

mRNA Protein Name
NM_030622.8 NP_085125.1 cytochrome P450 2S1 precursor

CYP2S1 Protein Structure

p450

p450: Cytochrome P450 (33 - 490)

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  • 504 a.a.
Protein Preferred Names Protein Names

cytochrome P450 2S1

cytochrome P450, family 2, subfamily S, polypeptide 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03467 CYP2S1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CYP2S1 MGD MGI:1921384
Macaca mulatta CYP2S1 VGNC VGNC:103641
Bos taurus CYP2S1 VGNC VGNC:110261
Rattus norvegicus CYP2S1 RGD RGD:1306078
Felis catus CYP2S1 VGNC VGNC:103487
Canis familiaris CYP2S1 VGNC VGNC:50356