LMCD1 - LIM and cysteine rich domains 1 Gene

Homo sapiens

Gene ID: 29995 | Gene type: protein coding

About LMCD1

Cytogenetic location: 3p25.3 Genomic coordinates (GRCh38): 3:8,501,823-8,574,668 (from NCBI)

This gene has 7 transcripts (splice variants), 202 orthologues and 3 paralogues. Broad expression in lung (RPKM 21.9), fat (RPKM 21.1) and 24 other tissues.

Summary

This gene encodes a member of the LIM-domain family of zinc finger proteins. The encoded protein contains an N-terminal cysteine-rich domain and two C-terminal LIM domains. The presence of LIM domains suggests involvement in protein-protein interactions. The protein may act as a co-regulator of transcription along with other transcription factors. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

LMCD1 Products(4)

mRNA	Protein	Name
NM_001278233.2	NP_001265162.1	LIM and cysteine-rich domains protein 1 isoform 2
NM_001278234.2	NP_001265163.1	LIM and cysteine-rich domains protein 1 isoform 3
NM_001278235.2	NP_001265164.1	LIM and cysteine-rich domains protein 1 isoform 4
NM_014583.4	NP_055398.1	LIM and cysteine-rich domains protein 1 isoform 1

LMCD1 Protein Structure

PET

LIM

0
100
200
300
365 a.a.

Protein Preferred Names

Protein Names

LIM and cysteine-rich domains protein 1

dyxin

Recombinant LMCD1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70926	LMCD1 Protein, Human (His)	Q9NZU5-1 (M1-S365)	≥95%

Related Diseases

Diseases

Alias

Lidocaine Allergy

Lidoderm Allergy	Lignocaine Allergy
Xylocaine Allergy

Mixed Cell Uveal Melanoma

Intraocular Mixed Cell Type Melanoma

Mixed Cell Type Uveal Melanoma

Posterior Uveal Melanoma

Medium/Large Size Posterior Uveal Melanoma	Small Size Posterior Uveal Melanoma
Ciliary Body And Choroid Melanoma, Medium/Large Size	Ciliary Body And Choroid Melanoma, Small Size

Orthostatic Intolerance

Mitral Valve Prolapse	Neurocirculatory Asthenia
Mitral Valve Prolapse Syndrome	Irritable Heart
Systolic Click-Murmur Syndrome	Soldiers Heart
Cardiovascular Malfunction Arising From Mental Factors	Cardiovascular Neurosis
Da Costa'S Syndrome	Krishaber'S Disease
Barlow'S Syndrome	Floppy Mitral Valve
Mitral Leaflet Syndrome	Myxomatous Mitral Valve Prolapse
Postural Orthostatic Tachycardia Syndrome Due To Net Deficiency	Familial Orthostatic Tachycardia Due To Norepinephrine Transporter Deficiency
Orthostatic Intolerance Due To Net Deficiency	Pots Due To Net Deficiency
OI	Intolerance, Orthostatic
Mitral Valve Prolapse, Familial, X-Linked	Ballooning Mitral Valve
Barlow Syndrome	Flail Mitral Leaflet
Myxomatous Mitral Valve	Mitral Valve Prolapse-Click Syndrome
Prolapsing Mitral Valve Leaflet Syndrome	Billowing Mitral Valve Leaflet
Posterior Mitral Leaflet Deformity	Ballooning Posterior Leaflet Syndrome
Blue Valve Syndrome	Floppy Mitral Valve Syndrome
Mitral Valvular Prolapse	Systolic Click Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07710	LMCD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	LMCD1	VGNC	VGNC:42714
Bos taurus	LMCD1	VGNC	VGNC:30926
Felis catus	LMCD1	VGNC	VGNC:68065
Macaca mulatta	LMCD1	VGNC	VGNC:74426
Rattus norvegicus	LMCD1	RGD	RGD:1308963
Mus musculus	LMCD1	MGD	MGI:1353635
Others	LMCD1	NCBI

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