1. Gene
  2. Ptgdr2 - prostaglandin D2 receptor 2 Gene

Ptgdr2 - prostaglandin D2 receptor 2 Gene

Rattus norvegicus

Also known as Gpr44

Gene ID: 309212 | Gene type: protein coding

About Ptgdr2

Primary_assembly 1: 207,587,917-207,589,213 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 206 orthologues, 14 paralogues and is associated with 7 phenotypes. Biased expression in Adrenal (RPKM 83.4), Lung (RPKM 29.9) and 8 other tissues.

Summary

Predicted to enable neuropeptide binding activity and Prostaglandin Receptor activity. Predicted to be involved in calcium-mediated signaling; chemotaxis; and neuropeptide signaling pathway. Predicted to act upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of male germ cell proliferation; and positive regulation of G protein-coupled receptor signaling pathway. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR2 (prostaglandin D2 receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ptgdr2 Products(1)

mRNA Protein Name
NM_001012070.1 NP_001012070.1 prostaglandin D2 receptor 2

Ptgdr2 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (31 - 313)

7tm_GPCRs

7tm_GPCRs: cd14964 (33 - 57)

7tm_GPCRs

7tm_GPCRs: cd14964 (65 - 86)

7tm_GPCRs

7tm_GPCRs: cd14964 (103 - 125)

7tm_GPCRs

7tm_GPCRs: cd14964 (148 - 164)

7tm_GPCRs

7tm_GPCRs: cd14964 (202 - 225)

7tm_GPCRs

7tm_GPCRs: cd14964 (243 - 265)

7tm_GPCRs

7tm_GPCRs: cd14964 (281 - 306)

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  • 403 a.a.
Protein Preferred Names Protein Names

prostaglandin D2 receptor 2

G protein-coupled receptor 44

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptgdr2 NCBI NCBI:11251