2. Gene
  3. HSP90AB1 - heat shock protein 90 alpha family class B member 1 Gene

HSP90AB1 - heat shock protein 90 alpha family class B member 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HSP84; HSPC2; HSPCB; D6S182; HSP90B

Gene ID: 3326 | Gene type: protein coding

About HSP90AB1

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:44,246,194-44,253,883 (from NCBI)

This gene has 4 transcripts (splice variants), 229 orthologues, 3 paralogues and is associated with 64 phenotypes. Ubiquitous expression in ovary (RPKM 514.6), brain (RPKM 324.0) and 25 other tissues.

Summary

This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric Apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]

HSP90AB1 Products(6)

mRNA Protein Name
NM_001271969.2 NP_001258898.1 heat shock protein HSP 90-beta isoform a
NM_001271970.2 NP_001258899.1 heat shock protein HSP 90-beta isoform a
NM_001271971.2 NP_001258900.1 heat shock protein HSP 90-beta isoform b
NM_001271972.2 NP_001258901.1 heat shock protein HSP 90-beta isoform c
NM_001371238.1 NP_001358167.1 heat shock protein HSP 90-beta isoform a
NM_007355.4 NP_031381.2 heat shock protein HSP 90-beta isoform a

HSP90AB1 Protein Structure

HATPase_c

HATPase_c: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (36 - 187)

HSP90

HSP90: Hsp90 protein (191 - 724)

  • 0
  • 200
  • 400
  • 600
  • 724 a.a.
Protein Preferred Names Protein Names

heat shock protein HSP 90-beta

HSP90-beta

Related Diseases

Diseases Alias
Powassan Encephalitis

Powassan Encephalitis Virus Infection
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06418 HSP90AB1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus HSP90AB1 VGNC VGNC:55918
Macaca mulatta HSP90AB1 VGNC VGNC:81078
Mus musculus HSP90AB1 MGD MGI:96247
Rattus norvegicus HSP90AB1 RGD RGD:1303075
Others HSP90AB1 NCBI