2. Gene
  3. JMJD8 - jumonji domain containing 8 Gene

JMJD8 - jumonji domain containing 8 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PP14397; C16orf20

Gene ID: 339123 | Gene type: protein coding

About JMJD8

This gene has 15 transcripts (splice variants), 190 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 36.7), kidney (RPKM 34.2) and 25 other tissues.

Summary

Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of sprouting angiogenesis; and regulation of glycolytic process. Located in endoplasmic reticulum lumen and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

JMJD8 Products(5)

mRNA Protein Name
NM_001005920.4 NP_001005920.3 jmjC domain-containing protein 8 isoform 1 precursor
NM_001323918.3 NP_001310847.2 jmjC domain-containing protein 8 isoform 2 precursor
NM_001323919.3 NP_001310848.2 jmjC domain-containing protein 8 isoform 3 precursor
NM_001323920.3 NP_001310849.2 jmjC domain-containing protein 8 isoform 4 precursor
NM_001323922.3 NP_001310851.2 jmjC domain-containing protein 8 isoform 5 precursor

JMJD8 Protein Structure

Cupin_8

Cupin_8: Cupin-like domain (81 - 270)

  • 0
  • 100
  • 200
  • 285 a.a.
Protein Preferred Names Protein Names

jmjC domain-containing protein 8

jumonji domain-containing protein 8

Related Diseases

Diseases Alias
Spinocerebellar Ataxia 48

SCA48
Spinocerebellar Ataxia, Autosomal Recessive 16

Autosomal Recessive Spinocerebellar Ataxia 16

SCAR16

Autosomal Recessive Cerebellar Ataxia Due To Stub1 Deficiency

Spinocerebellar Ataxia Autosomal Recessive Type 16

Spinocerebellar Ataxia, Autosomal Recessive, 16

Ataxia, Spinocerebellar, Autosomal Recessive, Type 16
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07041 JMJD8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus JMJD8 VGNC VGNC:63008
Bos taurus JMJD8 VGNC VGNC:58602
Macaca mulatta JMJD8 VGNC VGNC:73826
Rattus norvegicus JMJD8 RGD RGD:1307381
Mus musculus JMJD8 MGD MGI:1919356
Canis familiaris JMJD8 VGNC VGNC:42190