2. Gene
  3. KCTD8 - potassium channel tetramerization domain containing 8 Gene

KCTD8 - potassium channel tetramerization domain containing 8 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 386617 | Gene type: protein coding

About KCTD8

Cytogenetic location: 4p13 Genomic coordinates (GRCh38): 4:44,173,903-44,448,809 (from NCBI)

This gene has 2 transcripts (splice variants), 160 orthologues and 13 paralogues. Biased expression in brain (RPKM 3.7), thyroid (RPKM 1.4) and 7 other tissues.

Summary

Predicted to be involved in regulation of G protein-coupled receptor signaling pathway. Predicted to be located in cell projection; postsynaptic membrane; and presynaptic membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

KCTD8 Products(1)

mRNA Protein Name
NM_198353.3 NP_938167.1 BTB/POZ domain-containing protein KCTD8

KCTD8 Protein Structure

BTB_2

BTB_2: BTB/POZ domain (46 - 142)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 473 a.a.
Protein Preferred Names Protein Names

BTB/POZ domain-containing protein KCTD8

potassium channel tetramerisation domain containing 8

Related Diseases

Diseases Alias
Scalp-Ear-Nipple Syndrome

Finlay-Marks Syndrome

Sen Syndrome

SENS

Scalp Ear Nipple Syndrome

Hereditary Syndrome Of Lumpy Scalp, Odd Ears And Rudimentary Nipples

Hereditary Syndrome Of Lumpy Scalp, Odd Ears, And Rudimentary Nipples

Indian Childhood Cirrhosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07199 KCTD8 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KCTD8 VGNC VGNC:42311
Mus musculus KCTD8 MGD MGI:2443804
Rattus norvegicus KCTD8 RGD RGD:1312020
Macaca mulatta KCTD8 VGNC VGNC:73888
Bos taurus KCTD8 VGNC VGNC:59339
Felis catus KCTD8 VGNC VGNC:78518