SKOR1 - SKI family transcriptional corepressor 1 Gene

Homo sapiens

Also known as CORL1; LBXCOR1; FUSSEL15

Gene ID: 390598 | Gene type: protein coding

About SKOR1

Cytogenetic location: 15q23 Genomic coordinates (GRCh38): 15:67,825,509-67,834,582 (from NCBI)

This gene has 4 transcripts (splice variants), 246 orthologues and 3 paralogues. Low expression observed in reference dataset.

Summary

Enables SMAD binding activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of BMP signaling pathway. Located in dendrite and neuronal cell body. [provided by Alliance of Genome Resources, Apr 2022]

SKOR1 Products(1)

mRNA	Protein	Name
NM_001365915.1	NP_001352844.1	SKI family transcriptional corepressor 1

SKOR1 Protein Structure

Ski_Sno

c-SKI_SMAD_bind

0
200
400
600
800
965 a.a.

Protein Preferred Names

Protein Names

SKI family transcriptional corepressor 1

LBX1 corepressor 1

Related Diseases

Diseases

Alias

Restless Legs Syndrome

Wed	Willis-Ekbom Disease
Restless Leg Syndrome	Ekbom Syndrome
Wittmaack-Ekbom Syndrome	Willis Ekbom Disease
Ekbom'S Syndrome	Rls
Restless Legs	Restless Legs Syndrome, Susceptibility To

Periodic Limb Movement Disorder

Nocturnal Myoclonus Syndrome

Nocturnal Myoclonus

Osgood-Schlatter'S Disease

Osgood-Schlatter Disease	Juvenile Osteochondrosis Of Tibial Tubercle
Osteochondrosis	Osteochondritis Of Tibial Tubercle
Osteochondrosis Of Proximal Tibia	Aseptic Necrosis Of The Tibial Tubercle
Osteochondrosis Of The Tibial Tubercle	Osteochondritis Juvenilis

Essential Tremor

Benign Essential Tremor	Familial Tremor
Hereditary Essential Tremor	Essential Hereditary Tremor
Shaky Hand Syndrome	Benign Essential Tremor Syndrome
Tremor Hereditary Essential	Essential Tremor, Susceptibility To
Tremor, Hereditary Essential

Pulmonary Subvalvular Stenosis

Pulmonary Infundibular Stenosis	Congenital Infundibular Stenosis
Infundibular Pulmonic Stenosis	Infundibular Pulmonic Stenosis, Congenital
Subvalvular Pulmonic Stenosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12971	SKOR1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SKOR1	VGNC	VGNC:55143
Rattus norvegicus	SKOR1	RGD	RGD:1307687
Felis catus	SKOR1	VGNC	VGNC:104718
Mus musculus	SKOR1	MGD	MGI:2443473
Macaca mulatta	SKOR1	VGNC	VGNC:77544

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