LGALS2 - galectin 2 Gene

Homo sapiens

Also known as HL14

Gene ID: 3957 | Gene type: protein coding

About LGALS2

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:37,570,248-37,580,087 (from NCBI)

This gene has 2 transcripts (splice variants), 325 orthologues, 16 paralogues and is associated with 1 phenotype. Biased expression in gall bladder (RPKM 133.8), small intestine (RPKM 81.3) and 7 other tissues.

Summary

The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008]

LGALS2 Products(1)

mRNA	Protein	Name
NM_006498.3	NP_006489.1	galectin-2

LGALS2 Protein Structure

Gal-bind_lectin

0
100
132 a.a.

Protein Preferred Names

Protein Names

galectin-2

S-Lac lectin 2

Recombinant LGALS2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P700078AF	Animal-Free Galectin-2/LGALS2 Protein, Human (His)	P05162 (T2-E132)	≥95%
HY-P700301	Galectin-2/LGALS2 Protein, Human (GST)	P05162 (M1-E132)	≥95%

Related Diseases

Diseases

Alias

Myocardial Infarction

Heart Attack	Myocardial Infarction, Susceptibility To
Myocardial Infarction 1	Myocardial Infarction, Protection Against
Myocardial Infarction, Decreased Susceptibility To	Myocardial Infarction, Decreased
Myocardial Infarct	MCI1
Premature Myocardial Infarction	Myocardial Infarction, Susceptibility To, Type 1

Blackwater Fever

Black Water Fever	Hemoglobinuric, Malaria
Malarial Hemoglobinuria

Lipoprotein Quantitative Trait Locus

Coronary Artery Disease	Coronary Artery Anomaly
Coronary Artery Disease, Susceptibility To	Myocardial Ischemia
Congenital Anomaly Of Coronary Artery	Coronary Arteriosclerosis
Coronary Disease	Coronary Heart Disease
Coronary Artery Disorder	LPAQTL
Lpa Deficiency, Congenital	Coronary Artery Abnormality
Coronary Artery Anomaly, Congenital	Chd
Coronary Syndrome	Congenital Malformations Of Coronary Vessels
Malformation Of Coronary Vessels	Congenital Coronary Artery Anomaly
Congenital Coronary Artery Deformity	Congenital Coronary Artery Disorder
Abnormal Coronary Artery	Congenital Coronary Artery Malposition
Congenital Coronary Disease	Congenital Anomaly Of Coronary Arteries

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07603	LGALS2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	LGALS2	VGNC	VGNC:74254
Mus musculus	LGALS2	MGD	MGI:895068
Felis catus	LGALS2	VGNC	VGNC:68039
Canis familiaris	LGALS2	VGNC	VGNC:42647
Rattus norvegicus	LGALS2	RGD	RGD:621269
Bos taurus	LGALS2	VGNC	VGNC:50210
Macaca fascicularis	LGALS2	NCBI
Others	LGALS2	NCBI

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