2. Gene
  3. FOXB2 - forkhead box B2 Gene

FOXB2 - forkhead box B2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FKH4; bA159H20.4

Gene ID: 442425 | Gene type: protein coding

About FOXB2

Cytogenetic location: 9q21.2 Genomic coordinates (GRCh38): 9:77,019,655-77,020,953 (from NCBI)

This gene has 1 transcript (splice variant), 184 orthologues and 42 paralogues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

FOXB2 Products(1)

mRNA Protein Name
NM_001013735.1 NP_001013757.1 forkhead box protein B2

FOXB2 Protein Structure

Forkhead

Forkhead: Forkhead domain (13 - 108)

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  • 432 a.a.
Protein Preferred Names Protein Names

forkhead box protein B2

Related Diseases

Diseases Alias
Testicular Germ Cell Cancer

Germ Cell Tumor Of Testis

Testicular Germ Cell Tumor

Testicular Germ Cell Neoplasm

Testicular Malignant Germ Cell Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05040 FOXB2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris FOXB2 VGNC VGNC:40947
Macaca mulatta FOXB2 VGNC VGNC:72555
Bos taurus FOXB2 VGNC VGNC:55046
Mus musculus FOXB2 MGD MGI:1347468
Felis catus FOXB2 VGNC VGNC:102928
Rattus norvegicus FOXB2 RGD RGD:1585019