2. Gene
  3. NDUFB5 - NADH:ubiquinone oxidoreductase subunit B5 Gene

NDUFB5 - NADH:ubiquinone oxidoreductase subunit B5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SGDH; CISGDH

Gene ID: 4711 | Gene type: protein coding

About NDUFB5

Cytogenetic location: 3q26.33 Genomic coordinates (GRCh38): 3:179,604,794-179,627,647 (from NCBI)

This gene has 16 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in heart (RPKM 79.6), fat (RPKM 69.6) and 25 other tissues.

Summary

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the Enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

NDUFB5 Products(3)

mRNA Protein Name
NM_001199957.2 NP_001186886.1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 2
NM_001199958.2 NP_001186887.1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 3 precursor
NM_002492.4 NP_002483.1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform 1 precursor

NDUFB5 Protein Structure

NDUF_B5

NDUF_B5: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit (1 - 189)

  • 0
  • 100
  • 189 a.a.
Protein Preferred Names Protein Names

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09150 NDUFB5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NDUFB5 VGNC VGNC:31964
Rattus norvegicus NDUFB5 RGD RGD:1305909
Macaca mulatta NDUFB5 VGNC VGNC:75158
Felis catus NDUFB5 VGNC VGNC:68441
Mus musculus NDUFB5 MGD MGI:1913296