2. Gene
  3. Smyd3 - SET and MYND domain containing 3 Gene

Smyd3 - SET and MYND domain containing 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 498295 | Gene type: protein coding

About Smyd3

Primary_assembly 13: 90,709,270-91,266,253 reverse strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 231 orthologues, 5 paralogues and is associated with 5 phenotypes. Biased expression in Brain (RPKM 59.6), Kidney (RPKM 4.4) and 9 other tissues.

Summary

Predicted to enable RNA polymerase II complex binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and histone-lysine N-methyltransferase activity. Predicted to act upstream of or within several processes, including cellular response to dexamethasone stimulus; nucleosome assembly; and regulation of protein phosphorylation. Predicted to be located in cytosol and nucleoplasm. Orthologous to human SMYD3 (SET and MYND domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Smyd3 Products(1)

mRNA Protein Name
NM_001025762.1 NP_001020933.1 histone-lysine N-methyltransferase SMYD3

Smyd3 Protein Structure

SET_SMYD3

SET_SMYD3: cd19203 (4 - 267)

zf-MYND

zf-MYND: pfam01753 (48 - 86)

  • 0
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  • 400
  • 428 a.a.
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase SMYD3

SET and MYND domain-containing protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19324 EPZ031686 Inhibitor 99.71% Unkown
HY-104009A GSK2807 Trifluoroacetate Inhibitor 99.36% Unkown
HY-112080 BAY-6035 Inhibitor 99.82% Unkown
HY-151379 EM127 Inhibitor 98.37% Unkown
HY-128352 SMYD3-IN-1 Inhibitor 98.01% Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-152228 SMYD3-IN-2 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smyd3 NCBI NCBI:64754