2. Gene
  3. Mknk1 - MAPK interacting serine/threonine kinase 1 Gene

Mknk1 - MAPK interacting serine/threonine kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 500526 | Gene type: protein coding

About Mknk1

Primary_assembly 5: 129,318,170-129,357,639 forward strand.mRatBN7.2:CM026978.1

This gene has 2 transcripts (splice variants), 130 orthologues, 6 paralogues and is associated with 1 phenotype. Biased expression in Spleen (RPKM 76.3), Adrenal (RPKM 75.9) and 9 other tissues.

Summary

Enables protein serine/threonine kinase activity. Involved in peptidyl-serine phosphorylation and regulation of translational initiation. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mknk1 Products(1)

mRNA Protein Name
NM_001044267.1 NP_001037732.1 MAP kinase-interacting serine/threonine-protein kinase 1

Mknk1 Protein Structure

STKc_Mnk1

STKc_Mnk1: cd14174 (66 - 354)

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  • 446 a.a.
Protein Preferred Names Protein Names

MAP kinase-interacting serine/threonine-protein kinase 1

MAP kinase signal-integrating kinase 1

MAP kinase-interacting serine/threonine kinase 1

MAPK signal-integrating kinase 1

mnk1

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-15514 Merestinib Inhibitor 99.99% Phase 2
HY-15514A Merestinib dihydrochloride Inhibitor 99.36% Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08473 MKNK1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08474 Mknk1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08475 Mknk1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mknk1 NCBI NCBI:8569