2. Gene
  3. Mapk3 - mitogen activated protein kinase 3 Gene

Mapk3 - mitogen activated protein kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as p44; ERK1; ERT2; MNK1; Erk-1; Esrk1; MAPK1; Prkm3; p44erk1; p44mapk

Gene ID: 50689 | Gene type: protein coding

About Mapk3

Primary_assembly 1: 181,366,637-181,372,863 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 197 orthologues, 21 paralogues and is associated with 67 phenotypes. Biased expression in Lung (RPKM 21.4), Brain (RPKM 14.7) and 9 other tissues.

Summary

Enables ATP binding activity; MAP kinase activity; and scaffold protein binding activity. Involved in several processes, including arachidonic acid metabolic process; decidualization; and peptidyl-serine phosphorylation. Located in caveola; cytosol; and nucleoplasm. Part of protein-containing complex. Used to study gastric ulcer; middle cerebral artery infarction; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Mapk3 Products(1)

mRNA Protein Name
NM_017347.3 NP_059043.2 mitogen-activated protein kinase 3

Mapk3 Protein Structure

STKc_ERK1_2_like

STKc_ERK1_2_like: cd07849 (36 - 396)

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  • 406 a.a.
Protein Preferred Names Protein Names

mitogen-activated protein kinase 3

MAP kinase 1

MAP kinase 3

MAPK 1

MAPK 3

extracellular signal-regulated kinase 1

insulin-stimulated MAP2 kinase

microtubule-associated protein 2 kinase

mitogen-activated 3

mitogen-activated protein kinase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08113 MAPK3 Human Pre-designed siRNA Set A / Unkown
HY-RS08114 Mapk3 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08115 Mapk3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk3 NCBI NCBI:5595