VILL - villin like Gene

Homo sapiens

Gene ID: 50853 | Gene type: protein coding

About VILL

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:37,987,978-38,007,185 (from NCBI)

This gene has 10 transcripts (splice variants), 196 orthologues and 7 paralogues. Broad expression in stomach (RPKM 21.1), small intestine (RPKM 13.2) and 17 other tissues.

Summary

The protein encoded by this gene belongs to the villin/gelsolin family. It contains 6 gelsolin-like repeats and a headpiece domain. It may play a role in actin-bundling. [provided by RefSeq, Jul 2008]

VILL Products(5)

mRNA	Protein	Name
NM_001370264.1	NP_001357193.1	villin-like protein isoform 2
NM_001370265.1	NP_001357194.1	villin-like protein isoform 3
NM_001385038.1	NP_001371967.1	villin-like protein isoform 1
NM_001385039.1	NP_001371968.1	villin-like protein isoform 1
NM_015873.4	NP_056957.3	villin-like protein isoform 1

VILL Protein Structure

Gelsolin

VHP

0
200
400
600
800
856 a.a.

Protein Preferred Names

Protein Names

villin-like protein

Related Diseases

Diseases

Alias

Hyperekplexia

Hereditary Hyperekplexia	Kok Disease
Congenital Stiff Man Syndrome	Familial Startle Disease
Sthe	Stiff-Baby Syndrome
Hereditary Hyperexplexia	Startle Disease
Exaggerated Startle Reaction	Hyperexplexia Hereditary
Startle Disease, Familial	Startle Reaction, Exaggerated
Stiff-Man Syndrome, Congenital	Stiff-Person Syndrome, Congenital
Congenital Stiff-Man Syndrome	Congenital Stiff-Person Syndrome
Familial Hyperekplexia	Startle Syndrome
Stiff Baby Syndrome	Hyperekplexia, Hereditary
Stiff-Person Syndrome

Amyloidosis, Finnish Type

Finnish Type Amyloidosis	Meretoja Syndrome
Amyloidosis V	Amyloidosis, Meretoja Type
Amyloid Cranial Neuropathy With Lattice Corneal Dystrophy	Lattice Corneal Dystrophy Type Ii
Familial Amyloidosis, Finnish Type	Familial Amyloid Polyneuropathy Type Iv
Amyloidosis Due To Mutant Gelsolin	Agel Amyloidosis
Gelsolin Amyloidosis	Hereditary Gelsolin Amyloidosis
Lattice Corneal Dystrophy Type Ii Finnish	Gelsolin-Related Amyloidosis
Kymenlaakso Syndrome	Lattice Corneal Dystrophy, Gelsolin Type
Hereditary Amyloidosis, Finnish Type	Lattice Corneal Dystrophy Type 2
Amyloidosis 5	AMYL5
Agel	Familial Amyloidosis Finnish Type
Meretoja Type Amyloidosis	Type Iv Familial Amyloid Polyneuropathy
Familial Amyloid Polyneuropathy, Type V	Familial Amyloid Polyneuropathy, Type Iv

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15651	VILL Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	VILL	VGNC	VGNC:36795
Felis catus	VILL	VGNC	VGNC:102865
Canis familiaris	VILL	VGNC	VGNC:48262
Mus musculus	VILL	MGD	MGI:1201781
Rattus norvegicus	VILL	RGD	RGD:1304843
Macaca mulatta	VILL	VGNC	VGNC:79897
Others	VILL	NCBI