KLF3 - KLF transcription factor 3 Gene

Homo sapiens

Also known as BKLF

Gene ID: 51274 | Gene type: protein coding

About KLF3

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:38,664,199-38,701,517 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 22 paralogues. Ubiquitous expression in colon (RPKM 22.1), gall bladder (RPKM 19.2) and 25 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

KLF3 Products(1)

mRNA	Protein	Name
NM_016531.6	NP_057615.3	Krueppel-like factor 3

KLF3 Protein Structure

zf-H2C2_2

0
100
200
300
345 a.a.

Protein Preferred Names

Protein Names

Krueppel-like factor 3

CACCC-box-binding protein BKLF

Related Diseases

Diseases

Alias

Cutaneous Adenocystic Carcinoma

Adenoid Cystic Eccrine Carcinoma	Adenoid Cystic Carcinoma Of The Skin
Adenoid Cystic Eccrine Carcinoma Of Skin

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07340	KLF3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	KLF3	VGNC	VGNC:73840
Rattus norvegicus	KLF3	RGD	RGD:1593290
Felis catus	KLF3	VGNC	VGNC:63134
Canis familiaris	KLF3	VGNC	VGNC:42436
Mus musculus	KLF3	MGD	MGI:1342773
Bos taurus	KLF3	VGNC	VGNC:30630

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