TRMO - tRNA methyltransferase O Gene

Homo sapiens

Also known as NAP1; HSPC219; C9orf156

Gene ID: 51531 | Gene type: protein coding

About TRMO

This gene has 6 transcripts (splice variants) and 173 orthologues. Ubiquitous expression in thyroid (RPKM 2.2), lymph node (RPKM 1.5) and 25 other tissues.

Summary

Enables tRNA (adenine-N6-)-methyltransferase activity. Involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2022]

TRMO Products(7)

mRNA	Protein	Name
NM_001330725.2	NP_001317654.1	tRNA (adenine(37)-N6)-methyltransferase isoform 2
NM_001371657.1	NP_001358586.1	tRNA (adenine(37)-N6)-methyltransferase isoform 1
NM_001371658.1	NP_001358587.1	tRNA (adenine(37)-N6)-methyltransferase isoform 3
NM_001371659.1	NP_001358588.1	tRNA (adenine(37)-N6)-methyltransferase isoform 4
NM_001371660.1	NP_001358589.1	tRNA (adenine(37)-N6)-methyltransferase isoform 2
NM_001371661.1	NP_001358590.1	tRNA (adenine(37)-N6)-methyltransferase isoform 2
NM_016481.5	NP_057565.3	tRNA (adenine(37)-N6)-methyltransferase isoform 1

TRMO Protein Structure

UPF0066

0
100
200
300
400
441 a.a.

Protein Preferred Names

Protein Names

tRNA (adenine(37)-N6)-methyltransferase

Nef (lentivirus myristoylated factor) associated protein 1

Related Diseases

Diseases

Alias

Arthrogryposis, Distal, Type 6

Distal Arthrogryposis Type 6	DA6
Arthrogryposis-Like Hand Anomaly-Sensorineural Deafness Syndrome	Arthrogryposis And Sensorineural Deafness
Familial Hand Abnormality And Sensori-Neural Deafness	Arthrogryposis-Like Hand Anomaly And Sensorineural Deafness
Arthrogryposis-Like Hand Anomaly-Sensorineural Hearing Loss Syndrome

Thiamine-Responsive Megaloblastic Anemia Syndrome

TRMA	Rogers Syndrome
Thiamine-Responsive Myelodysplasia	Thiamine-Responsive Anemia Syndrome
Thiamine Metabolism Dysfunction Syndrome 1	Thmd1
Megaloblastic Anemia, Thiamine-Responsive, With Diabetes Mellitus And Sensorineural Deafness	Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Deafness
Thiamine Responsive Megaloblastic Anemia Syndrome	Megaloblastic Anemia Thiamine-Responsive With Diabetes Mellitus And Sensorineural Deafness
Thiamine-Responsive Megaloblastic Anemia	Thiamine-Responsive Anaemia Syndrome
Thiamine-Responsive Megaloblastic Anaemia Syndrome	Thiamine-Responsive Megaloblastic Anaemia With Diabetes Mellitus And Sensorineural Deafness
Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Hearing Loss

Cleft Palate, Isolated

Cleft Palate	Isolated Cleft Palate
CPI	Cp
Palatoschisis	Cleft Palate Isolated
Uranostaphyloschisis	Congenital Fissure Of Palate
Cleft Of Secondary Palate

Galloway-Mowat Syndrome

Galloway Mowat Syndrome	Galloway Syndrome
Hiatal Hernia-Microcephaly-Nephrosis, Galloway Type	Microcephaly Nephrosis Syndrome
Microcephaly, Hiatal Hernia, And Nephrotic Syndrome	Nephrosis Neuronal Dysmigration Syndrome
Microcephaly-Hiatus Hernia-Nephrotic Syndrome	Nephrosis-Neuronal Dysmigration Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15085	TRMO Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TRMO	VGNC	VGNC:79907
Mus musculus	TRMO	MGD	MGI:1922003
Bos taurus	TRMO	VGNC	VGNC:36364
Rattus norvegicus	TRMO	RGD	RGD:1305420
Felis catus	TRMO	VGNC	VGNC:66564
Canis familiaris	TRMO	VGNC	VGNC:47849