KLF13 - KLF transcription factor 13 Gene

Homo sapiens

Also known as BTEB3; FKLF2; NSLP1; RFLAT1; RFLAT-1

Gene ID: 51621 | Gene type: protein coding

About KLF13

Cytogenetic location: 15q13.3 Genomic coordinates (GRCh38): 15:31,326,835-31,435,665 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 118 orthologues, 22 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 34.5), lung (RPKM 27.2) and 24 other tissues.

Summary

KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]

KLF13 Products(2)

mRNA	Protein	Name
NM_001302461.2	NP_001289390.1	Krueppel-like factor 13 isoform 2
NM_015995.4	NP_057079.2	Krueppel-like factor 13 isoform 1

KLF13 Protein Structure

zf-H2C2_2

0
100
200
288 a.a.

Protein Preferred Names

Protein Names

Krueppel-like factor 13

BTE-binding protein 3

Related Diseases

Diseases

Alias

Chromosome 15q13.3 Deletion Syndrome

Chromosome 15q13.3 Microdeletion Syndrome	15q13.3 Microdeletion Syndrome
15q13.3 Microdeletion	Microdeletion 15q13.3 Syndrome
Del(15)(Q13.3)	Monosomy 15q13.3

Tricuspid Valve Stenosis

Tricuspid Stenosis	Tricuspid Stricture
Tricuspid Valve Stricture	Tricuspid Insufficiency With Obstruction
Tricuspid Insufficiency With Stenosis

Heart Disease

Heart Failure	Congenital Heart Disease
Heart Diseases	Congenital Heart Defects
Congenital Heart Defect	Heart Malformation
Congenital Anomaly Of Heart	Heart Defect
Heart-Congenital Defect	Congenital Heart Disorder
Heart Defects Congenital	Heart Defects, Congenital
Heart Defects	Heart Disease, Congenital
Disease, Heart, Congenital	Congestive Heart Failure

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07334	KLF13 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	KLF13	RGD	RGD:1565099
Bos taurus	KLF13	VGNC	VGNC:106796
Mus musculus	KLF13	MGD	MGI:1354948
Macaca mulatta	KLF13	VGNC	VGNC:84365
Felis catus	KLF13	VGNC	VGNC:80941

Name
Email *

	Sorry, but the email address you supplied was invalid.