2. Gene
  3. NUDT9 - nudix hydrolase 9 Gene

NUDT9 - nudix hydrolase 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NUDT10

Gene ID: 53343 | Gene type: protein coding

About NUDT9

Cytogenetic location: 4q22.1 Genomic coordinates (GRCh38): 4:87,422,573-87,459,455 (from NCBI)

This gene has 8 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in kidney (RPKM 6.8), prostate (RPKM 6.3) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This Enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

NUDT9 Products(3)

mRNA Protein Name
NM_001248011.2 NP_001234940.1 ADP-ribose pyrophosphatase, mitochondrial isoform c precursor
NM_024047.5 NP_076952.1 ADP-ribose pyrophosphatase, mitochondrial isoform a precursor
NM_198038.3 NP_932155.1 ADP-ribose pyrophosphatase, mitochondrial isoform b

NUDT9 Protein Structure

NUDIX

NUDIX: NUDIX domain (198 - 325)

  • 0
  • 100
  • 200
  • 300
  • 350 a.a.
Protein Preferred Names Protein Names

ADP-ribose pyrophosphatase, mitochondrial

ADP-ribose diphosphatase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09675 NUDT9 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NUDT9 VGNC VGNC:75555
Bos taurus NUDT9 VGNC VGNC:32343
Rattus norvegicus NUDT9 RGD RGD:1359522
Canis familiaris NUDT9 VGNC VGNC:44037
Felis catus NUDT9 VGNC VGNC:78541
Mus musculus NUDT9 MGD MGI:1921417