CDCA8 - cell division cycle associated 8 Gene

Homo sapiens

Also known as BOR; DasraB; MESRGP; BOREALIN

Gene ID: 55143 | Gene type: protein coding

About CDCA8

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:37,692,516-37,709,719 (from NCBI)

This gene has 2 transcripts (splice variants) and 210 orthologues. Biased expression in testis (RPKM 14.3), bone marrow (RPKM 12.4) and 13 other tissues.

Summary

This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16. [provided by RefSeq, Apr 2013]

CDCA8 Products(2)

mRNA	Protein	Name
NM_001256875.2	NP_001243804.1	borealin
NM_018101.4	NP_060571.1	borealin

CDCA8 Protein Structure

Nbl1_Borealin_N

Borealin

0
100
200
280 a.a.

Protein Preferred Names

Protein Names

borealin

Dasra B

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02317	CDCA8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CDCA8	RGD	RGD:1566306
Mus musculus	CDCA8	MGD	MGI:1196274
Bos taurus	CDCA8	VGNC	VGNC:27088
Macaca mulatta	CDCA8	VGNC	VGNC:70714
Felis catus	CDCA8	VGNC	VGNC:60670
Canis familiaris	CDCA8	VGNC	VGNC:39017

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