AGPAT5 - 1-acylglycerol-3-phosphate O-acyltransferase 5 Gene

Homo sapiens

Also known as LPAATE; LPLAT5; 1AGPAT5

Gene ID: 55326 | Gene type: protein coding

About AGPAT5

Cytogenetic location: 8p23.1 Genomic coordinates (GRCh38): 8:6,708,642-6,761,503 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 211 orthologues and 4 paralogues. Broad expression in testis (RPKM 16.0), brain (RPKM 13.8) and 23 other tissues.

Summary

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. A pseudogene of this gene is present on the Y chromosome. [provided by RefSeq, Aug 2014]

AGPAT5 Products(1)

mRNA	Protein	Name
NM_018361.5	NP_060831.2	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

AGPAT5 Protein Structure

Acyltransferase

0
100
200
300
364 a.a.

Protein Preferred Names

Protein Names

1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1-AGP acyltransferase 5

Related Diseases

Diseases

Alias

Fetal Akinesia Deformation Sequence 4

FADS4	Fetal Akinesia Deformation Sequence Syndrome 4
Akinesia, Fetal, Deformation Sequence, Type 4

Fetal Akinesia Deformation Sequence 1

Fetal Akinesia Deformation Sequence	Fads
Fetal Akinesia Sequence	FADS1
Arthrogryposis Multiplex Congenita With Pulmonary Hypoplasia	Pena-Shokeir Syndrome Type 1
Fetal Akinesia Deformation Sequence Syndrome	Arthrogryposis Multiplex Congenita-Pulmonary Hypoplasia Syndrome
Arthrogryposis Multiplex Congenita Pulmonary Hypoplasia	Pena-Shokeir Syndrome, Type I
Foetal Akinesia Deformation Sequence Syndrome	Foetal Akinesia Sequence
Fetal Akinesia Deformation Sequence Syndrome 1	Pena-Shokeir Syndrome, Type 1
Pena Shokeir Syndrome, Type 1	Akinesia, Fetal, Deformation Sequence
Akinesia, Fetal, Deformation Sequence, Type 1	Pena-Shokeir Syndrome Type I

Congenital Generalized Lipodystrophy

Berardinelli-Seip Congenital Lipodystrophy	Berardinelli-Seip Syndrome
Brunzell Syndrome	Bscl
Generalized Lipodystrophy	Lipodystrophy, Congenital Generalized
Seip Syndrome	Total Lipodystrophy
Cgl	Lipoatrophic Diabetes
Lipodystrophy, Generalized, Congenital	Familial Generalized Lipodystrophy
Congenital Generalized Lipodystrophy Type 2	Lipoatrophic Diabetes Mellitus
Familial Partial Lipodystrophy, Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00460	AGPAT5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	AGPAT5	RGD	RGD:1306405
Canis familiaris	AGPAT5	VGNC	VGNC:49767
Bos taurus	AGPAT5	VGNC	VGNC:25738
Felis catus	AGPAT5	VGNC	VGNC:59688
Macaca mulatta	AGPAT5	VGNC	VGNC:69655
Mus musculus	AGPAT5	MGD	MGI:1196345

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