NAGK - N-acetylglucosamine kinase Gene

Homo sapiens

Also known as GNK; HSA242910

Gene ID: 55577 | Gene type: protein coding

About NAGK

Cytogenetic location: 2p13.3 Genomic coordinates (GRCh38): 2:71,068,296-71,079,808 (from NCBI)

This gene has 29 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in spleen (RPKM 27.6), esophagus (RPKM 26.3) and 25 other tissues.

Summary

This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian Enzyme which recovers amino sugars. [provided by RefSeq, Nov 2011]

NAGK Products(4)

mRNA	Protein	Name
NM_001330425.3	NP_001317354.1	N-acetyl-D-glucosamine kinase isoform 2
NM_001330426.2	NP_001317355.1	N-acetyl-D-glucosamine kinase isoform 2
NM_001365466.2	NP_001352395.1	N-acetyl-D-glucosamine kinase isoform 2
NM_017567.6	NP_060037.4	N-acetyl-D-glucosamine kinase isoform 1

NAGK Protein Structure

BcrAD_BadFG

0
100
200
300
344 a.a.

Protein Preferred Names

Protein Names

N-acetyl-D-glucosamine kinase

epididymis secretory sperm binding protein

Related Diseases

Diseases

Alias

Nonaka Myopathy

Gne Myopathy	Hibm
Distal Myopathy With Rimmed Vacuoles	Hereditary Inclusion Body Myopathy
Ibm2	Inclusion Body Myopathy, Quadriceps-Sparing
Qsm	Dmrv
Distal Myopathy, Nonaka Type	Inclusion Body Myopathy 2
Inclusion Body Myopathy, Autosomal Recessive	NM
Nonaka Distal Myopathy	Myopathy, Distal, With Or Without Rimmed Vacuoles
Inclusion Body Myopathy, Hereditary, Autosomal Recessive	Inclusion Body Myopathy Type 2
Quadriceps-Sparing Myopathy	Quadriceps Sparing Myopathy
Rimmed Vacuole Myopathy	Inclusion Body Myopathy 2, Autosomal Recessive, Formerly
Ibm2, Formerly	Hibm2
Hereditary Inclusion Body Myopathy Type 2	Inclusion Body Myopathy 2, Autosomal Recessive
Myopathy, Distal, With Rimmed Vacuoles	Inclusion Body Myopathy Autosomal Recessive
Myopathy, Inclusion Body, Type 2	Myopathy, Nonaka

Sialuria

Sialuria, French Type	French Type Sialuria
Sialuria French Type	Sialic Acid Storage Disease
Sialic Acid Storage Disease, Finnish Type	Infantile Sialic Acid Storage Disease

Chronic Monocytic Leukemia

Leukemia, Myeloid

Leukemia, Monocytic, Chronic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09010	NAGK Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	NAGK	RGD	RGD:1305057
Macaca mulatta	NAGK	VGNC	VGNC:74977
Bos taurus	NAGK	VGNC	VGNC:31868
Mus musculus	NAGK	MGD	MGI:1860418
Felis catus	NAGK	VGNC	VGNC:63713

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