PLGRKT - plasminogen receptor with a C-terminal lysine Gene

Homo sapiens

Also known as AD025; MDS030; C9orf46; PLG-RKT; Plg-R(KT)

Gene ID: 55848 | Gene type: protein coding

About PLGRKT

Cytogenetic location: 9p24.1 Genomic coordinates (GRCh38): 9:5,357,971-5,438,377 (from NCBI)

This gene has 4 transcripts (splice variants) and 186 orthologues. Ubiquitous expression in colon (RPKM 12.9), duodenum (RPKM 11.8) and 24 other tissues.

Summary

Predicted to be involved in positive regulation of plasminogen activation. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PLGRKT Products(1)

mRNA	Protein	Name
NM_018465.4	NP_060935.2	plasminogen receptor (KT)

PLGRKT Protein Structure

DUF2368

0
100
147 a.a.

Protein Preferred Names

Protein Names

plasminogen receptor (KT)

5033414D02Rik

Related Diseases

Diseases

Alias

Plasminogen Deficiency, Type I

Hypoplasminogenemia	Dysplasminogenemia
Plasminogen Deficiency Type I	Congenital Plasminogen Deficiency
Ligneous Conjunctivitis	Type 1 Plasminogen Deficiency
Plasminogen Deficiency Type 1	Plasminogen Deficiency
PLGD	Plasminogen Deficiency Type Ii
Deficiency, Plasminogen, Type I

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10705	PLGRKT Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PLGRKT	VGNC	VGNC:33028
Macaca mulatta	PLGRKT	VGNC	VGNC:76098
Mus musculus	PLGRKT	MGD	MGI:1915009
Canis familiaris	PLGRKT	VGNC	VGNC:44689
Felis catus	PLGRKT	VGNC	VGNC:102964
Rattus norvegicus	PLGRKT	RGD	RGD:1306839

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