PSG6 - pregnancy specific beta-1-glycoprotein 6 Gene

Homo sapiens

Also known as PSG10; PSGGB; PSBG-6; PSBG-10; PSBG-12

Gene ID: 5675 | Gene type: protein coding

About PSG6

Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38): 19:42,902,086-42,917,894 (from NCBI)

This gene has 9 transcripts (splice variants), 628 orthologues and 24 paralogues. Restricted expression toward placenta (RPKM 62.8).

Summary

This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

PSG6 Products(2)

mRNA	Protein	Name
NM_001031850.4	NP_001027020.1	pregnancy-specific beta-1-glycoprotein 6 isoform b precursor
NM_002782.5	NP_002773.1	pregnancy-specific beta-1-glycoprotein 6 isoform a precursor

PSG6 Protein Structure

V-set

Ig_2

0
100
200
300
400
435 a.a.

Protein Preferred Names

Protein Names

pregnancy-specific beta-1-glycoprotein 6

PS-beta-G-10

Recombinant PSG6 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77161	PSG6 Protein, Human (sf9, His)	Q00889-2/NP_001027020 (Q35-H424)	≥95%

Related Diseases

Diseases

Alias

Chorioangioma

Placental Hemangioma