2. Gene
  3. NMRAL1 - NmrA like redox sensor 1 Gene

NMRAL1 - NmrA like redox sensor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HSCARG; SDR48A1

Gene ID: 57407 | Gene type: protein coding

About NMRAL1

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:4,461,694-4,476,337 (from NCBI)

This gene has 18 transcripts (splice variants), 1 gene allele and 113 orthologues. Ubiquitous expression in prostate (RPKM 6.2), ovary (RPKM 6.2) and 25 other tissues.

Summary

This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular Antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]

NMRAL1 Products(6)

mRNA Protein Name
NM_001305141.3 NP_001292070.1 nmrA-like family domain-containing protein 1 isoform 1
NM_001305142.3 NP_001292071.1 nmrA-like family domain-containing protein 1 isoform 1
NM_001351994.2 NP_001338923.1 nmrA-like family domain-containing protein 1 isoform 1
NM_001351995.2 NP_001338924.1 nmrA-like family domain-containing protein 1 isoform 2
NM_001351996.2 NP_001338925.1 nmrA-like family domain-containing protein 1 isoform 3
NM_020677.6 NP_065728.1 nmrA-like family domain-containing protein 1 isoform 1

NMRAL1 Protein Structure

NmrA

NmrA: NmrA-like family (7 - 237)

  • 0
  • 100
  • 200
  • 299 a.a.
Protein Preferred Names Protein Names

nmrA-like family domain-containing protein 1

NmrA-like family domain containing 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09385 NMRAL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NMRAL1 VGNC VGNC:32134
Macaca mulatta NMRAL1 VGNC VGNC:75252
Rattus norvegicus NMRAL1 RGD RGD:1311451
Mus musculus NMRAL1 MGD MGI:1915074
Canis familiaris NMRAL1 VGNC VGNC:103694
Felis catus NMRAL1 VGNC VGNC:63841