1. Gene
  2. DDX55 - DEAD-box helicase 55 Gene

DDX55 - DEAD-box helicase 55 Gene

Homo sapiens
Gene ID: 57696 | Gene type: protein coding

About DDX55

This gene has 13 transcripts (splice variants), 206 orthologues and 38 paralogues. Ubiquitous expression in lymph node (RPKM 4.3), bone marrow (RPKM 4.0) and 25 other tissues.

Summary

This gene encodes a member of protein family containing a characteristic Asp-Glu-Ala-Asp (DEAD) motif. These proteins are putative RNA helicases, and may be involved in a range of nuclear processes including translational initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Multiple alternatively spliced transcript variants have been found for this gene. Pseudogenes have been identified on chromosomes 1 and 12. [provided by RefSeq, Feb 2016]

DDX55 Products(1)

mRNA Protein Name
NM_020936.3 NP_065987.1 ATP-dependent RNA helicase DDX55

DDX55 Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (33 - 212)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (292 - 363)

DUF4217

DUF4217: Domain of unknown function (DUF4217) (403 - 465)

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Protein Preferred Names Protein Names

ATP-dependent RNA helicase DDX55

DEAD (Asp-Glu-Ala-Asp) box polypeptide 55

Related Diseases

Diseases Alias
Atrial Septal Defect 1

ASD1

Atrial Heart Septal Defect 1

Asd

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus DDX55 VGNC VGNC:27977
Macaca mulatta DDX55 VGNC VGNC:71681
Felis catus DDX55 VGNC VGNC:61416
Mus musculus DDX55 MGD MGI:1915098
Rattus norvegicus DDX55 RGD RGD:2324094
Canis familiaris DDX55 VGNC VGNC:39865