2. Gene
  3. P2ry4 - pyrimidinergic receptor P2Y4 Gene

P2ry4 - pyrimidinergic receptor P2Y4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as P2Y4

Gene ID: 63843 | Gene type: protein coding

About P2ry4

Primary_assembly X: 65,683,232-65,721,748 reverse strand.mRatBN7.2:CM026994.1

This gene has 4 transcripts (splice variants), 168 orthologues, 13 paralogues and is associated with 3 phenotypes. Biased expression in Adrenal (RPKM 16.9), Lung (RPKM 14.4) and 9 other tissues.

Summary

Enables ATP binding activity. Involved in regulation of presynaptic cytosolic calcium ion concentration and regulation of synaptic vesicle exocytosis. Located in apical plasma membrane and basolateral plasma membrane. Is active in glutamatergic synapse. Is integral component of presynaptic active zone membrane. Orthologous to human P2RY4 (pyrimidinergic receptor P2Y4). [provided by Alliance of Genome Resources, Apr 2022]

P2ry4 Products(1)

mRNA Protein Name
NM_031680.1 NP_113868.1 P2Y purinoceptor 4

P2ry4 Protein Structure

7tmA_P2Y4

7tmA_P2Y4: cd15374 (31 - 312)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (31 - 58)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (65 - 90)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (103 - 133)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (145 - 167)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (192 - 221)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (233 - 263)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (280 - 305)

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  • 361 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 4

P2Y ATP receptor 4

purinergic receptor P2Y, G-protein coupled 4

pyrimidinergic receptor P2Y, G-protein coupled, 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09931 P2RY4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09932 P2ry4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09933 P2ry4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2ry4 NCBI NCBI:5030