2. Gene
  3. SRPK2 - SRSF protein kinase 2 Gene

SRPK2 - SRSF protein kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SFRSK2

Gene ID: 6733 | Gene type: protein coding

About SRPK2

Cytogenetic location: 7q22.3 Genomic coordinates (GRCh38): 7:105,114,740-105,399,357 (from NCBI)

This gene has 15 transcripts (splice variants), 236 orthologues and 19 paralogues. Broad expression in testis (RPKM 31.3), brain (RPKM 21.9) and 24 other tissues.

Summary

Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including nucleic acid metabolic process; peptidyl-serine phosphorylation; and regulation of viral genome replication. Located in chromatin; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

SRPK2 Products(12)

mRNA Protein Name
NM_001278273.2 NP_001265202.1 SRSF protein kinase 2 isoform b precursor
NM_001350738.2 NP_001337667.1 SRSF protein kinase 2 isoform b
NM_001350739.2 NP_001337668.1 SRSF protein kinase 2 isoform c
NM_001350740.2 NP_001337669.1 SRSF protein kinase 2 isoform d
NM_001350741.2 NP_001337670.1 SRSF protein kinase 2 isoform e
NM_001350742.2 NP_001337671.1 SRSF protein kinase 2 isoform f
NM_001350743.2 NP_001337672.1 SRSF protein kinase 2 isoform g
NM_001350744.2 NP_001337673.1 SRSF protein kinase 2 isoform g
NM_001350745.2 NP_001337674.1 SRSF protein kinase 2 isoform h
NM_001350746.2 NP_001337675.1 SRSF protein kinase 2 isoform i
NM_182691.3 NP_872633.1 SRSF protein kinase 2 isoform b precursor
NM_182692.3 NP_872634.1 SRSF protein kinase 2 isoform a

SRPK2 Protein Structure

Pkinase

Pkinase: Protein kinase domain (81 - 223)

Pkinase

Pkinase: Protein kinase domain (524 - 686)

  • 0
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  • 688 a.a.
Protein Preferred Names Protein Names

SRSF protein kinase 2

SFRS protein kinase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148518 MSC-1186 Inhibitor 99.42% Unkown
HY-113831 CLK1/2-IN-3 Inhibitor / Unkown
HY-RS13778 SRPK2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SRPK2 MGD MGI:1201408
Felis catus SRPK2 VGNC VGNC:65688
Bos taurus SRPK2 VGNC VGNC:35289
Canis familiaris SRPK2 VGNC VGNC:46811
Rattus norvegicus SRPK2 RGD RGD:1305107
Macaca mulatta SRPK2 VGNC VGNC:81764
Others SRPK2 NCBI