Gpr183 - G protein-coupled receptor 183 Gene

Rattus norvegicus

Also known as Ebi2

Gene ID: 679975 | Gene type: protein coding

About Gpr183

Primary_assembly 15: 99,036,367-99,050,559 reverse strand.mRatBN7.2:CM026988.1

This gene has 2 transcripts (splice variants), 207 orthologues, 5 paralogues and is associated with 5 phenotypes. Biased expression in Spleen (RPKM 29.5), Thymus (RPKM 19.8) and 9 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity and oxysterol binding activity. Predicted to be involved in several processes, including dendritic cell homeostasis; leukocyte chemotaxis; and leukocyte differentiation. Predicted to be located in plasma membrane. Orthologous to human GPR183 (G protein-coupled receptor 183). [provided by Alliance of Genome Resources, Apr 2022]

Gpr183 Products(1)

mRNA	Protein	Name
NM_001109386.1	NP_001102856.1	G-protein coupled receptor 183

Gpr183 Protein Structure

7tmA_EBI2

0
100
200
300
357 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor 183

EBV-induced G-protein coupled receptor 2	Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)
epstein-Barr virus-induced G-protein coupled receptor 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-113962	7α,25-Dihydroxycholesterol	Agonist	≥99.0%	Unkown
HY-147222	SAE-14	Antagonist	98.26%	Unkown
HY-162011	GPR183 antagonist-2	Antagonist	99.96%	Unkown
HY-113962S	7α,25-Dihydroxycholesterol-d6		/	Unkown
HY-157939	GPR183 antagonist-3	Antagonist	/	Unkown
HY-RS05690	GPR183 Human Pre-designed siRNA Set A		/	Unkown
HY-RS05691	Gpr183 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS05692	Gpr183 Rat Pre-designed siRNA Set A		/	Unkown
HY-400897	7α,25-Dihydroxycholesterol intermediate-1		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpr183	NCBI	NCBI:1880

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