2. Gene
  3. Ido2 - indoleamine 2,3-dioxygenase 2 Gene

Ido2 - indoleamine 2,3-dioxygenase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IDO-2; Indol1

Gene ID: 681319 | Gene type: protein coding

About Ido2

Primary_assembly 16: 67,459,190-67,496,324 forward strand.mRatBN7.2:CM026989.1

This gene has 1 transcript (splice variant), 91 orthologues and is associated with 3 phenotypes. Restricted expression toward (RPKM 55.6).

Summary

Predicted to enable indoleamine 2,3-dioxygenase activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in 'de novo' NAD biosynthetic process from tryptophan and tryptophan catabolic process to kynurenine. Predicted to be active in cytoplasm. Orthologous to human IDO2 (indoleamine 2,3-dioxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ido2 Products(4)

mRNA Protein Name
XM_039095218.1 XP_038951146.1 indoleamine 2,3-dioxygenase 2 isoform X4
XM_008771375.2 XP_008769597.2 indoleamine 2,3-dioxygenase 2 isoform X1
XM_039095217.1 XP_038951145.1 indoleamine 2,3-dioxygenase 2 isoform X3
XM_039095215.1 XP_038951143.1 indoleamine 2,3-dioxygenase 2 isoform X2

Ido2 Protein Structure

IDO

IDO: pfam01231 (14 - 398)

  • 0
  • 100
  • 200
  • 300
  • 405 a.a.
Protein Preferred Names Protein Names

indoleamine 2,3-dioxygenase 2

indoleamine 2,3-dioxygenase-like protein 1

indoleamine-pyrrole 2,3 dioxygenase-like 1

indoleamine-pyrrole 2,3-dioxygenase-like protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100687 GNF-PF-3777 Inhibitor 98.56% Unkown
HY-151093 IDO2-IN-1 Inhibitor 98.86% Unkown
HY-145280 IDO1/2-IN-1 Inhibitor 98.06% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ido2 NCBI NCBI:169355