FGFR1 - fibroblast growth factor receptor 1 Gene

Macaca mulatta

Gene ID: 700126 | Gene type: protein coding

About FGFR1

Primary_assembly 8: 38,877,386-38,935,926 reverse strand.Mmul_10:CM014343.1

This gene has 6 transcripts (splice variants), 293 orthologues and 53 paralogues.

FGFR1 Products(1)

mRNA	Protein	Name
NM_001266647.1	NP_001253576.1	fibroblast growth factor receptor 1 precursor

FGFR1 Protein Structure

IgI_1_FGFR

IgI_2_FGFR

PTKc_FGFR1

0
200
400
600
822 a.a.

Protein Preferred Names

Protein Names

fibroblast growth factor receptor 1

basic fibroblast growth factor receptor 1

Recombinant FGFR1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75769	FGFR-1 Protein, Rhesus Macaque (HEK293, Fc)	H9FRD4 (M1-Y283)	≥95%
HY-P75770	FGFR-1 Protein, Rhesus Macaque (HEK293, His)	H9FRD4/NP_001253576.1 (R22-Y283)	≥95%

Related Agents

Approval

Bioactive Molecules (15)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10981	Lenvatinib	Inhibitor	99.84%	Yes
HY-50904	Nintedanib	Inhibitor	99.94%	Yes
HY-12047	Ponatinib	Inhibitor	99.43%	Yes
HY-18708	Erdafitinib	Inhibitor	99.66%	Unkown
HY-13311	Infigratinib	Inhibitor	99.72%	Yes
HY-109099	Pemigatinib	Inhibitor	99.73%	Yes
HY-10208	Pazopanib	Inhibitor	99.91%	Yes
HY-100818	Futibatinib	Inhibitor	99.65%	Unkown
HY-11106	Nintedanib esylate	Inhibitor	99.95%	Yes
HY-10981A	Lenvatinib mesylate	Inhibitor	99.86%	Yes
HY-N0060	Ferulic acid	Inhibitor	99.87%	Yes
HY-12009	Pazopanib Hydrochloride	Inhibitor	99.88%	Yes
HY-12297	Sulfatinib	Inhibitor	98.65%	Unkown
HY-108766	Ponatinib hydrochloride	Inhibitor	99.55%	Yes
HY-13311A	Infigratinib phosphate	Inhibitor	99.74%	Yes

Clinical Phase

Bioactive Molecules (20)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13330	Fexagratinib	Inhibitor	99.85%	Phase 3
HY-50905	Dovitinib	Inhibitor	99.94%	Phase 3
HY-100019	Rogaratinib	Inhibitor	99.86%	Phase 3
HY-10517	Orantinib	Inhibitor	99.21%	Phase 3
HY-15391	Lucitanib	Inhibitor	98.94%	Phase 3
HY-10207	Dovitinib lactate	Inhibitor	99.62%	Phase 3
HY-B0062	Dovitinib lactate hydrate	Inhibitor	/	Phase 3
HY-101568	Roblitinib	Inhibitor	99.74%	Phase 2
HY-10987A	ENMD-2076	Inhibitor	99.12%	Phase 2
HY-19957	Zoligratinib	Inhibitor	99.76%	Phase 2
HY-19981	Derazantinib	Inhibitor	99.28%	Phase 2
HY-10987	ENMD-2076 Tartrate	Inhibitor	99.42%	Phase 2
HY-10186	TG 100801	Inhibitor	98.60%	Phase 2
HY-101466A	E7090 succinate	Inhibitor	99.17%	Phase 2
HY-10187	TG 100801 Hydrochloride	Inhibitor	/	Phase 2
HY-10339	KW-2449	Inhibitor	99.69%	Phase 1
HY-13304	LY2874455	Inhibitor	98.03%	Phase 1
HY-119367	ODM-203	Inhibitor	99.91%	Phase 1
HY-19983	ASP5878	Inhibitor	99.86%	Phase 1
HY-101768	PRN1371	Inhibitor	99.43%	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99614	Fazpilodemab	Agonist	99.00%	Phase 2

Pre-clinical Phase

Bioactive Molecules (41)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10321	PD173074	Inhibitor	99.70%	Unkown
HY-10407	SU 5402	Inhibitor	99.38%	Unkown
HY-101296	PD-166866	Inhibitor	99.89%	Unkown
HY-12823	BLU9931	Inhibitor	99.95%	Unkown
HY-15599	SSR128129E	Inhibitor	99.85%	Unkown
HY-18602	FIIN-2	Inhibitor	99.63%	Unkown
HY-145231	FGFR2-IN-2	Inhibitor	98.09%	Unkown
HY-10185	TG 100572 Hydrochloride	Inhibitor	98.96%	Unkown
HY-148779	FGFR3-IN-5	Inhibitor	99.28%	Unkown
HY-114311	FGFR1/DDR2 inhibitor 1	Inhibitor	98.26%	Unkown
HY-131908	CPL304110	Inhibitor	99.68%	Unkown
HY-100315	Tyrosine kinase-IN-1	Inhibitor	99.34%	Unkown
HY-100434	PD-161570	Inhibitor	99.04%	Unkown
HY-101466	E7090	Inhibitor	99.64%	Unkown
HY-13737	R1530	Inhibitor	99.06%	Unkown
HY-15813	FIIN-1	Inhibitor	99.11%	Unkown
HY-16025	EOC317	Inhibitor	98.05%	Unkown
HY-100491	H3B-6527	Inhibitor	≥98.0%	Unkown
HY-12965	S49076	Inhibitor	99.71%	Unkown
HY-156019	FGFR1 inhibitor-10	Inhibitor	98.92%	Unkown
HY-118203	SU4984	Inhibitor	99.14%	Unkown
HY-112345	PD-089828	Inhibitor	98.07%	Unkown
HY-18603	FIIN-3	Inhibitor	99.66%	Unkown
HY-108933	JK-P3	Inhibitor	99.72%	Unkown
HY-12047S	Ponatinib-d8	Inhibitor	99.91%	Unkown
HY-10517A	(Z)-Orantinib	Inhibitor	99.02%	Unkown
HY-10184	TG 100572	Inhibitor	/	Unkown
HY-101544	ARQ 069	Inhibitor	/	Unkown
HY-151903S	FGFR2/3-IN-1	Inhibitor	/	Unkown
HY-139376	FGFR1 inhibitor-2	Inhibitor	/	Unkown
HY-147713	FGFR3-IN-1	Inhibitor	/	Unkown
HY-150026	Multi-kinase-IN-2	Inhibitor	/	Unkown
HY-152146	HDAC-IN-50	Inhibitor	/	Unkown
HY-150652	FGFR-IN-8	Inhibitor	/	Unkown
HY-152104	FGFR-IN-9	Inhibitor	/	Unkown
HY-149415	Multi-kinase-IN-5	Inhibitor	/	Unkown
HY-155028	FGFR-IN-11	Inhibitor	/	Unkown
HY-143272	FGFR1 inhibitor-6	Inhibitor	/	Unkown
HY-147715	FGFR3-IN-3	Inhibitor	/	Unkown
HY-142921	FGFR-IN-2	Inhibitor	/	Unkown
HY-15599A	SSR128129E free acid	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	FGFR1	NCBI	NCBI:2260

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