ATP13A3 - ATPase 13A3 Gene

Homo sapiens

Also known as PPH5; AFURS1

Gene ID: 79572 | Gene type: protein coding

About ATP13A3

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:194,402,677-194,494,334 (from NCBI)

This gene has 15 transcripts (splice variants), 285 orthologues and 21 paralogues. Ubiquitous expression in thyroid (RPKM 24.7), appendix (RPKM 18.3) and 25 other tissues.

Summary

ATP13A3 is a member of the P-type ATPase family of proteins that transport a variety of cations across membranes. Other P-type ATPases include ATP7B (MIM 606882) and ATP7A (MIM 300011).[supplied by OMIM, Aug 2008]

ATP13A3 Products(3)

mRNA	Protein	Name
NM_001367549.1	NP_001354478.1	polyamine-transporting ATPase 13A3 isoform 2
NM_001374836.1	NP_001361765.1	polyamine-transporting ATPase 13A3 isoform 3
NM_024524.4	NP_078800.3	polyamine-transporting ATPase 13A3 isoform 1

ATP13A3 Protein Structure

P5-ATPase

Cation_ATPase_N

E1-E2_ATPase

HAD

0
200
400
600
800
1000
1226 a.a.

Protein Preferred Names

Protein Names

polyamine-transporting ATPase 13A3

ATPase family homolog up-regulated in senescence cells 1

Related Diseases

Diseases

Alias

Pulmonary Hypertension, Primary, 5

Pulmonary Hypertension, Primary, 5, Autosomal Recessive	PPH5
Hypertension, Pulmonary, Primary, Type 5

Pulmonary Hypertension, Primary, 1

Pulmonary Arterial Hypertension	Pah
Idiopathic Pulmonary Arterial Hypertension	Idiopathic Pulmonary Hypertension
Primary Pulmonary Hypertension	PPH1
Pulmonary Hypertension, Primary, Fenfluramine Or Dexfenfluramine-Associated	Pulmonary Hypertension, Familial Primary, 1, With Or Without Hht
Pph	Familial Primary Pulmonary Hypertension
Sporadic Primary Pulmonary Hypertension	Pht
Fpah	Familial Pulmonary Arterial Hypertension
Hereditary Pulmonary Arterial Hypertension	Heritable Pulmonary Arterial Hypertension
Ayerza Syndrome	Fpph
Ppht	Ipah
Primary Pulmonary Arterial Hypertension	Pulmonary Hypertension, Familial Primary
Hypertension, Pulmonary, Primary, Type 1	Ayerza'S Syndrome
Pah - [Pulmonary Arterial Hypertension]	Arrillaga Ayerza Syndrome

Pulmonary Venoocclusive Disease

Pulmonary Veno-Occlusive Disease	Obstructive Disease Of The Pulmonary Veins
Pvod	Isolated Pulmonary Venous Sclerosis
Venous Form Of Primary Pulmonary Hypertension	Pulmonary Venoocclusive Disease 1, Autosomal Dominant

Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension

Small Patella Syndrome	Ischiopatellar Dysplasia
Coxopodopatellar Syndrome	Scott-Taor Syndrome
Sps	Ischiocoxopodopatellar Syndrome
Patella Aplasia, Coxa Vara, And Tarsal Synostosis	ICPPS
Congenital Coxa Vara, Patella Aplasia And Tarsal Synostosis	Coxo-Podo-Patellar Syndrome
Patella Aplasia, Coxa Vara, Tarsal Synostosis	Coxopodipatellar Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01180	ATP13A3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ATP13A3	VGNC	VGNC:38243
Rattus norvegicus	ATP13A3	RGD	RGD:1590881
Felis catus	ATP13A3	VGNC	VGNC:60017
Mus musculus	ATP13A3	MGD	MGI:2685387
Macaca mulatta	ATP13A3	VGNC	VGNC:70117
Bos taurus	ATP13A3	VGNC	VGNC:26279

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