1. Gene
  2. MCTP1 - multiple C2 and transmembrane domain containing 1 Gene

MCTP1 - multiple C2 and transmembrane domain containing 1 Gene

Homo sapiens
Gene ID: 79772 | Gene type: protein coding

About MCTP1

Cytogenetic location: 5q15 Genomic coordinates (GRCh38): 5:94,703,690-95,285,094 (from NCBI)

This gene has 18 transcripts (splice variants), 270 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 4.3), fat (RPKM 3.5) and 22 other tissues.

Summary

Enables calcium ion binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; negative regulation of endocytosis; and negative regulation of response to oxidative stress. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

MCTP1 Products(20)

mRNA Protein Name
NM_001002796.5 NP_001002796.1 multiple C2 and transmembrane domain-containing protein 1 isoform S
NM_001297777.3 NP_001284706.1 multiple C2 and transmembrane domain-containing protein 1 isoform 3
NM_001393535.1 NP_001380464.1 multiple C2 and transmembrane domain-containing protein 1 isoform 4
NM_001393536.1 NP_001380465.1 multiple C2 and transmembrane domain-containing protein 1 isoform 5
NM_001393537.1 NP_001380466.1 multiple C2 and transmembrane domain-containing protein 1 isoform 6
NM_001393538.1 NP_001380467.1 multiple C2 and transmembrane domain-containing protein 1 isoform 7
NM_001393539.1 NP_001380468.1 multiple C2 and transmembrane domain-containing protein 1 isoform 8
NM_001393540.1 NP_001380469.1 multiple C2 and transmembrane domain-containing protein 1 isoform 9
NM_001393541.1 NP_001380470.1 multiple C2 and transmembrane domain-containing protein 1 isoform 10
NM_001393542.1 NP_001380471.1 multiple C2 and transmembrane domain-containing protein 1 isoform 11
NM_001393543.1 NP_001380472.1 multiple C2 and transmembrane domain-containing protein 1 isoform 12
NM_001393544.1 NP_001380473.1 multiple C2 and transmembrane domain-containing protein 1 isoform 13
NM_001393545.1 NP_001380474.1 multiple C2 and transmembrane domain-containing protein 1 isoform 14
NM_001393546.1 NP_001380475.1 multiple C2 and transmembrane domain-containing protein 1 isoform 15
NM_001393547.1 NP_001380476.1 multiple C2 and transmembrane domain-containing protein 1 isoform 16
NM_001393548.1 NP_001380477.1 multiple C2 and transmembrane domain-containing protein 1 isoform 17
NM_001393549.1 NP_001380478.1 multiple C2 and transmembrane domain-containing protein 1 isoform 18
NM_001393550.1 NP_001380479.1 multiple C2 and transmembrane domain-containing protein 1 isoform 19
NM_001393551.1 NP_001380480.1 multiple C2 and transmembrane domain-containing protein 1 isoform 20
NM_024717.7 NP_078993.4 multiple C2 and transmembrane domain-containing protein 1 isoform L

MCTP1 Protein Structure

C2

C2: C2 domain (263 - 343)

C2

C2: C2 domain (473 - 553)

C2

C2: C2 domain (628 - 707)

PRT_C

PRT_C: Plant phosphoribosyltransferase C-terminal (872 - 974)

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Protein Preferred Names Protein Names

multiple C2 and transmembrane domain-containing protein 1

multiple C2 domains, transmembrane 1

Orthologs Information

Species Symbol Source ID
Mus musculus MCTP1 MGD MGI:1926021
Canis familiaris MCTP1 VGNC VGNC:43094
Macaca mulatta MCTP1 VGNC VGNC:74589
Rattus norvegicus MCTP1 RGD RGD:1305199
Bos taurus MCTP1 VGNC VGNC:106816
Felis catus MCTP1 VGNC VGNC:97503