MCMBP - minichromosome maintenance complex binding protein Gene

Homo sapiens

Also known as MCM-BP; C10orf119

Gene ID: 79892 | Gene type: protein coding

About MCMBP

Cytogenetic location: 10q26.11 Genomic coordinates (GRCh38): 10:119,829,440-119,873,581 (from NCBI)

This gene has 5 transcripts (splice variants) and 202 orthologues. Ubiquitous expression in placenta (RPKM 15.0), appendix (RPKM 14.1) and 25 other tissues.

Summary

This gene encodes a protein which is a component of the hexameric minichromosome maintenance (MCM) complex which regulates initiation and elongation of DNA. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

MCMBP Products(3)

mRNA	Protein	Name
NM_001256378.2	NP_001243307.1	mini-chromosome maintenance complex-binding protein isoform 2
NM_001256379.2	NP_001243308.1	mini-chromosome maintenance complex-binding protein isoform 3
NM_024834.4	NP_079110.1	mini-chromosome maintenance complex-binding protein isoform 1

MCMBP Protein Structure

MCM_bind

0
100
200
300
400
500
600
642 a.a.

Protein Preferred Names

Protein Names

mini-chromosome maintenance complex-binding protein

MCM-binding protein

Related Diseases

Diseases

Alias

Humeroradial Synostosis

Humero-Radial Fusion	Humero-Radial Synostosis
Ramer Ladda Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08243	MCMBP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MCMBP	MGD	MGI:1920977
Bos taurus	MCMBP	VGNC	VGNC:31316
Felis catus	MCMBP	VGNC	VGNC:63416
Rattus norvegicus	MCMBP	RGD	RGD:1306730
Macaca mulatta	MCMBP	VGNC	VGNC:74583

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