2. Gene
  3. MINDY3 - MINDY lysine 48 deubiquitinase 3 Gene

MINDY3 - MINDY lysine 48 deubiquitinase 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CARP; DERP5; my042; MST126; FAM188A; MSTP126; C10orf97

Gene ID: 80013 | Gene type: protein coding

About MINDY3

Cytogenetic location: 10p13 Genomic coordinates (GRCh38): 10:15,778,174-15,860,507 (from NCBI)

This gene has 6 transcripts (splice variants), 216 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 5.8), adrenal (RPKM 4.8) and 25 other tissues.

Summary

The protein encoded by this gene contains a caspase-associated recruitment domain and may function in Apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric Cancer risk. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]

MINDY3 Products(2)

mRNA Protein Name
NM_001318330.2 NP_001305259.1 ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform b precursor
NM_024948.4 NP_079224.1 ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform a

MINDY3 Protein Structure

DUF4205

DUF4205: Domain of unknown function (DUF4205) (28 - 300)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 445 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase MINDY-3

CARD-containing protein

Related Diseases

Diseases Alias
Pollen Allergy

Hay Fever
Fish Allergy

Allergy To Fish
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08453 MINDY3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MINDY3 VGNC VGNC:74811
Mus musculus MINDY3 MGD MGI:1914210
Felis catus MINDY3 VGNC VGNC:63512
Bos taurus MINDY3 VGNC VGNC:31478
Rattus norvegicus MINDY3 RGD RGD:1309605
Canis familiaris MINDY3 VGNC VGNC:49794