ELL3 - elongation factor for RNA polymerase II 3 Gene

Homo sapiens

Gene ID: 80237 | Gene type: protein coding

About ELL3

Cytogenetic location: 15q15.3 Genomic coordinates (GRCh38): 15:43,772,620-43,776,966 (from NCBI)

This gene has 8 transcripts (splice variants), 356 orthologues and 5 paralogues. Ubiquitous expression in thyroid (RPKM 75.8), prostate (RPKM 58.8) and 25 other tissues.

Summary

Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription, DNA-templated and transcription by RNA polymerase II. Located in several cellular components, including chromosome; cytosol; and nuclear lumen. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022]

ELL3 Products(1)

mRNA	Protein	Name
NM_025165.3	NP_079441.1	RNA polymerase II elongation factor ELL3

ELL3 Protein Structure

ELL

Occludin_ELL

0
100
200
300
397 a.a.

Protein Preferred Names

Protein Names

RNA polymerase II elongation factor ELL3

elongation factor RNA polymerase II-like 3

Related Diseases

Diseases

Alias

Cns Neuroblastoma With Foxr2 Activation

Central Nervous System Neuroblastoma With Foxr2 Activation	Cns Nb-Foxr2
Cns Neuroblastoma, Foxr2-Activated

Central Nervous System Neuroblastoma

Central Nervous System Germ Cell Tumor

Central Nervous System Germ Cell Tumour	Germ Cell Tumor Of The Cns
Germ Cell Tumour Of The Cns

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04310	ELL3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ELL3	MGD	MGI:2673679
Macaca mulatta	ELL3	VGNC	VGNC:72087
Canis familiaris	ELL3	VGNC	VGNC:40308
Felis catus	ELL3	VGNC	VGNC:61814
Bos taurus	ELL3	VGNC	VGNC:28437
Rattus norvegicus	ELL3	RGD	RGD:1309917