GRPEL1 - GrpE like 1, mitochondrial Gene

Homo sapiens

Also known as GrpE; HMGE; mt-GrpE#1

Gene ID: 80273 | Gene type: protein coding

About GRPEL1

Cytogenetic location: 4p16.1 Genomic coordinates (GRCh38): 4:7,058,895-7,068,064 (from NCBI)

This gene has 4 transcripts (splice variants), 221 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 26.2), kidney (RPKM 13.9) and 25 other tissues.

Summary

Enables identical protein binding activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial matrix and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

GRPEL1 Products(1)

mRNA	Protein	Name
NM_025196.4	NP_079472.1	grpE protein homolog 1, mitochondrial precursor

GRPEL1 Protein Structure

GrpE

0
100
200
217 a.a.

Protein Preferred Names

Protein Names

grpE protein homolog 1, mitochondrial

GrpE-like protein cochaperone

Related Diseases

Diseases

Alias

Human Monocytic Ehrlichiosis

Ehrlichiosis Chafeensis	Hme
Human Ehrlichial Infection, Human Monocytic Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05845	GRPEL1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	GRPEL1	MGD	MGI:1334417
Macaca mulatta	GRPEL1	VGNC	VGNC:106588
Rattus norvegicus	GRPEL1	RGD	RGD:70947
Felis catus	GRPEL1	VGNC	VGNC:107337
Bos taurus	GRPEL1	VGNC	VGNC:29665
Canis familiaris	GRPEL1	VGNC	VGNC:41517

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