ILKAP - ILK associated serine/threonine phosphatase Gene

Homo sapiens

Also known as PP2CD; PPM1O; ILKAP2; ILKAP3; PP2C-DELTA

Gene ID: 80895 | Gene type: protein coding

About ILKAP

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:238,170,402-238,203,695 (from NCBI)

This gene has 12 transcripts (splice variants), 200 orthologues and 16 paralogues. Ubiquitous expression in bone marrow (RPKM 11.1), testis (RPKM 10.3) and 25 other tissues.

Summary

The protein encoded by this gene is a protein serine/threonine Phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of Integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq, Jul 2008]

ILKAP Products(1)

mRNA	Protein	Name
NM_030768.3	NP_110395.1	integrin-linked kinase-associated serine/threonine phosphatase 2C

ILKAP Protein Structure

PP2C

0
100
200
300
392 a.a.

Protein Preferred Names

Protein Names

integrin-linked kinase-associated serine/threonine phosphatase 2C

integrin-linked kinase associated phosphatase

Recombinant ILKAP Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76438	ILKAP/PP2C delta Protein, Human (HEK293, His)	Q9H0C8 (M1-H392)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06788	ILKAP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ILKAP	VGNC	VGNC:30178
Rattus norvegicus	ILKAP	RGD	RGD:620128
Mus musculus	ILKAP	MGD	MGI:1914694
Canis familiaris	ILKAP	VGNC	VGNC:42002
Macaca mulatta	ILKAP	VGNC	VGNC:73604
Felis catus	ILKAP	VGNC	VGNC:80246
Others	ILKAP	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.