AIF1L - allograft inflammatory factor 1 like Gene

Homo sapiens

Also known as IBA2; C9orf58

Gene ID: 83543 | Gene type: protein coding

About AIF1L

This gene has 10 transcripts (splice variants), 199 orthologues and 1 paralogue. Biased expression in kidney (RPKM 130.1), spleen (RPKM 121.3) and 8 other tissues.

Summary

Enables actin filament binding activity. Predicted to be involved in actin filament bundle assembly and ruffle assembly. Located in actin Cytoskeleton and focal adhesion. Colocalizes with actin filament. Biomarker of breast Cancer. [provided by Alliance of Genome Resources, Apr 2022]

AIF1L Products(3)

mRNA	Protein	Name
NM_001185095.2	NP_001172024.1	allograft inflammatory factor 1-like isoform 3
NM_001185096.2	NP_001172025.1	allograft inflammatory factor 1-like isoform 4
NM_031426.4	NP_113614.1	allograft inflammatory factor 1-like isoform 1

Protein Preferred Names

Protein Names

allograft inflammatory factor 1-like

ionized calcium binding adapter molecule 2

Related Diseases

Diseases

Alias

Cutaneous Adenocystic Carcinoma

Adenoid Cystic Eccrine Carcinoma	Adenoid Cystic Carcinoma Of The Skin
Adenoid Cystic Eccrine Carcinoma Of Skin

Bronchus Cancer

Malignant Neoplasm Of Bronchus And Lung	Bronchus Carcinoma
Bronchogenic Carcinoma	Malignant Neoplasm Of Bronchus Or Lung
Bc - Bronchogenic Carcinoma	Carcinoma, Bronchogenic
Bronchial Neoplasms

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00491	AIF1L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	AIF1L	VGNC	VGNC:25760
Felis catus	AIF1L	VGNC	VGNC:102896
Mus musculus	AIF1L	MGD	MGI:1919598
Rattus norvegicus	AIF1L	RGD	RGD:1305081
Macaca mulatta	AIF1L	VGNC	VGNC:103237
Canis familiaris	AIF1L	VGNC	VGNC:37736

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